Blog

  • Levocetirizine: Uses, Dosage, Side Effects and Precautions

    Levocetirizine: Uses, Dosage, Side Effects and Precautions

    Levocetirizine is the generic name of an antihistamine used for allergy symptoms. It is a prescription medicine in India, sold under many brand names as tablets and as a syrup.

    Those products are made by many different companies. The active ingredient is the same across them, but strength, form, pack size and price are not.

    What is levocetirizine? 

     Levocetirizine

    Levocetirizine is an antihistamine. MedlinePlus[1] explains that it works by blocking the action of histamine, a substance in the body that causes allergic symptoms.

    The NHS[2] describes antihistamines as medicines used to relieve the symptoms of allergies such as hay fever, hives, conjunctivitis and reactions to insect bites or stings. That page covers the antihistamine class and does not name levocetirizine.

    Its status in India is set by the Drugs Rules, 1945[3]. Levocetirizine appears at entry 285 in Schedule H, the schedule of prescription drugs. Rule 97 requires the pack to carry the symbol Rx and a warning against retail sale without a doctor’s prescription.

    What are the main levocetirizine uses? 

    levocetirizine uses

    Levocetirizine is used for allergy symptoms. MedlinePlus lists sneezing, a runny nose, itching of the nose or throat, and red, itchy or watery eyes. It also lists the symptoms of urticaria, or hives.

    DailyMed’s prescribing information[4] sets out three approved indications. They are relief of symptoms of seasonal allergic rhinitis, relief of symptoms of perennial allergic rhinitis, and treatment of the uncomplicated skin manifestations of chronic idiopathic urticaria.

    Those indications sit on a United States label. They do not describe the approved indications of any Indian product.

    Popular brands containing levocetirizine 

    Several levocetirizine brands are sold in India. The company names below are those shown on the Medkart listing for each pack.

    Brand Name Active Ingredient Available Strengths / Forms* Manufacturer / Company
    Vozet Levocetirizine 5 mg tablets Dr Reddy’s Laboratories Limited
    Levorid Levocetirizine 5 mg tablets Cipla Pharmaceutical Company Limited
    Lecope Levocetirizine 5 mg tablets Mankind Pharma Limited
    Xevor Levocetirizine 5 mg tablets Abbott Health Care Private Limited
    Zipcet Levocetirizine 5 mg tablets Zydus Lifesciences Limited
    Levocet Levocetirizine 5 mg tablets Hetero Drugs Limited

    Examples of listed strengths and forms, not a complete catalogue. Product ranges can change.

    Availability and pack size differ between products. The range sold under any one brand can change.

    Levocetirizine composition and available strengths 

    Levocetirizine composition

    Levocetirizine tablets are commonly sold at a strength of 5 mg. DailyMed’s prescribing information describes a 5 mg tablet scored so that a 2.5 mg amount can be given. DailyMed’s oral solution label[5] describes a strength of 2.5 mg per 5 ml.

    A strength such as levocetirizine 5 mg describes the amount of active ingredient in that product. It is product information, not a dosing instruction.

    Medkart’s listings for levocetirizine 5 mg and levocetirizine 2.5 mg per 5 ml show tablets and syrups from a range of manufacturers.

    Also Read: Montek LC Tablet: Indications, Dosage Guide & Safety Precautions

    How is levocetirizine dosage decided? 

    Levocetirizine dosage

    There is no one dose that applies to every levocetirizine prescription. Age and kidney function both come into it.

    DailyMed’s prescribing information gives 5 mg once daily in the evening for adults and children aged 12 and over, and notes that some patients are controlled on 2.5 mg. It gives 2.5 mg once daily in the evening for children aged 6 to 11 years.

    The oral solution label gives 1.25 mg once daily in the evening for children aged 6 months to 5 years. The prescribing information also sets lower amounts for adults and adolescents whose kidney function is reduced, worked out from creatinine clearance.

    MedlinePlus advises taking levocetirizine at the same time every day, and says it should be taken exactly as directed. What applies to one person is a decision for the prescriber.

    What are the common levocetirizine side effects? 

    levocetirizine side effects

    Sleepiness is the most commonly reported side effect. DailyMed’s prescribing information reports somnolence in 6 per cent of adults and adolescents aged 12 and over.

    The same source reports nasopharyngitis in 4 per cent, fatigue in 4 per cent, dry mouth in 2 per cent and pharyngitis in 1 per cent. For children aged 6 to 12 years it reports fever in 4 per cent, cough in 3 per cent, somnolence in 3 per cent and nosebleeds in 2 per cent.

    MedlinePlus lists sleepiness and tiredness as its common effects. It lists other effects that call for a doctor straight away, including:

    • Hives
    • Rash
    • Itching
    • Swelling of the arms, hands, feet, ankles or lower legs

    DailyMed advises against hazardous work needing full mental alertness, such as driving or operating machinery.

    Who should be careful with levocetirizine? 

    Kidney function is what most often changes the picture. DailyMed’s prescribing information states that levocetirizine is substantially excreted by the kidneys, so the risk of adverse reactions is greater where kidney function is impaired.

    Why kidney function matters 

    Because the kidneys do most of the clearing, reduced kidney function leaves more of the medicine in the body. DailyMed lists end-stage renal disease, at a creatinine clearance below 10 ml per minute, and treatment by haemodialysis among its contraindications. It also contraindicates use in children aged 6 months to 11 years whose kidney function is impaired.

    The over-the-counter Xyzal Allergy 24HR label[6] is stricter still for self-treatment. It says the product should not be used at all by anyone with kidney disease.

    Situation What to do
    Reduced kidney function DailyMed’s prescribing information sets lower amounts based on creatinine clearance. MedlinePlus says to tell the doctor about any past or present kidney disease.
    End-stage renal disease or dialysis DailyMed lists both among its contraindications, so the medicine is not given in those circumstances.
    A previous reaction to cetirizine DailyMed lists known hypersensitivity to levocetirizine or to cetirizine as a contraindication. The Xyzal Allergy 24HR label says the product should not be used by anyone who has reacted to an antihistamine containing cetirizine.
    Trouble passing urine The Xyzal Allergy 24HR label says to ask a doctor before use if there has ever been trouble urinating or emptying the bladder, and to stop use if that difficulty occurs.
    Pregnancy or breastfeeding MedlinePlus says to tell the doctor about pregnancy or plans to become pregnant, and advises against breastfeeding while taking levocetirizine. The Xyzal Allergy 24HR label says the same about breastfeeding and directs anyone pregnant to ask a health professional.
    Adults aged 65 and over The Xyzal Allergy 24HR label directs adults aged 65 and over to ask a doctor before use.

    The NHS adds that people who are pregnant or breastfeeding, older people, and people with heart, liver or kidney disease or epilepsy should check before taking an antihistamine.

    Generic levocetirizine vs brand-name levocetirizine 

    Generic levocetirizine vs brand-name levocetirizine

    Generic and branded levocetirizine contain the same active ingredient. The US FDA[7] states that a generic medicine matches the brand-name medicine on active ingredient, strength, dosage form and route of administration, and is bioequivalent to it.

    The FDA adds that approved generics provide the same clinical benefit and risks as their brand-name counterparts. That is the U.S. FDA standard, and an India-specific regulatory source is needed before making the same claim about an Indian product.

    Products can still differ in manufacturer, inactive ingredients, appearance and price. The same active ingredient and strength alone do not prove that two products are interchangeable. A doctor or pharmacist should confirm any switch between brands.

    Buy or compare levocetirizine tablets on Medkart 

    Medkart sells levocetirizine products online in several brands and forms, and lists them as prescription items. Medkart states that the medicines it sells are sourced from WHO-GMP certified manufacturers.

    Medkart’s medicine comparison tool places products side by side, and the medicines index lists what is in stock. The details a reader can compare include:

    • Active ingredient
    • Strength
    • Dosage form
    • Manufacturer
    • Pack size
    • Current price

    Any suggested alternative should be discussed with a doctor or pharmacist before changing a prescribed medicine.

    Key takeaways 

    • Levocetirizine is an antihistamine that works by blocking the action of histamine.
    • Its approved uses include seasonal allergic rhinitis, perennial allergic rhinitis and chronic idiopathic urticaria.
    • Levocetirizine is listed at entry 285 in Schedule H of India’s Drugs Rules, 1945, which makes it a prescription drug.
    • A strength such as levocetirizine 5 mg is product information, not an instruction about how much to take.
    • Labelling gives 5 mg once daily in the evening for adults and children aged 12 and over, with smaller amounts for younger children.
    • Somnolence is the most commonly reported side effect, at 6 per cent in adults and adolescents.
    • Levocetirizine is substantially excreted by the kidneys, so reduced kidney function changes what is appropriate.
    • Generic and branded levocetirizine share the same active ingredient, but two individual products are not automatically interchangeable.

    FAQs: Common Questions About Levocetirizine 

    Q. How is levocetirizine different from cetirizine? 

    The sources used for this article do not compare the two directly. What the labelling does show is that they are treated as closely linked. DailyMed lists a known reaction to either one as a reason not to take levocetirizine. A doctor or pharmacist is the right person to ask which of the two suits a particular case.

    Q. What happens if a dose of levocetirizine is missed? 

    It depends on how close the next dose is. MedlinePlus says a missed dose should be taken as soon as it is remembered, but skipped if it is almost time for the next one. It advises returning to the regular schedule after that rather than taking two doses close together.

    Q. Can levocetirizine be taken with food? 

    Yes. MedlinePlus says levocetirizine can be taken with or without food. It also says to take it at the same time each day, which matters more for keeping the schedule steady than any particular meal does.

    Q. Is it safe to drink alcohol while taking levocetirizine? 

    It is better avoided. DailyMed advises against using alcohol or other central nervous system depressants alongside levocetirizine. The Xyzal Allergy 24HR label adds that alcohol, sedatives and tranquillisers increase drowsiness, which is the reason the combination is discouraged.

    Q. Can levocetirizine be taken for a long time? 

    That is a decision for the prescriber. MedlinePlus says levocetirizine should be taken exactly as directed, and not in larger amounts or more often than prescribed. It also notes that severe itching can develop after the medicine is stopped, particularly where it has been taken regularly for months or years.

    Q. What should someone do if too much levocetirizine is taken? 

    Get medical help. The Xyzal Allergy 24HR label says that in an overdose, medical help should be sought or a poison control centre contacted straight away. That instruction names a United States helpline, so in India the step is to contact a doctor, a pharmacist or a hospital.

    References 

    Medical disclaimer: This article provides general information and does not replace advice from a doctor or pharmacist. Levocetirizine is an antihistamine listed in Schedule H of India’s Drugs Rules, 1945, so levocetirizine products in India are prescription medicines. Brands with the same composition should only be substituted under the guidance of a healthcare professional or pharmacist because product details and approved indications can differ.

  • Jamun (Indian Blackberry): Uses, Benefits and Side Effects

    Jamun (Indian Blackberry): Uses, Benefits and Side Effects

    Jamun is the fruit of the tree Syzygium cumini. It is a small purple fruit, eaten fresh in season across India, and its leaves, seeds and bark have a long record of traditional use.

    Most of what is written about jamun concerns blood sugar. The research behind those claims is uneven, and it matters which part of the plant a given study used.

    What are the traditional uses of jamun? 

    Jamun’s Traditional Wellness Uses

    Different parts of the plant have different traditional uses. A 2015 review in Frontiers in Pharmacology[1] records the leaves being used for skin complaints, digestive complaints, constipation and diabetes.

    The same review records the fruits being used for pharyngitis and disorders of the spleen, and the bark being used as an astringent, an anthelmintic and a carminative. It notes that the seeds are used as an astringent and a diuretic, and especially in the treatment of diabetes.

    A review of the genus Syzygium[2] records S. cumini being used for diarrhoea, dysentery, menorrhagia, asthma and ulcers. That review draws mainly on animal models rather than studies in people.

    What does jamun fruit contain? 

    Jamun’s Nutrient-Rich Goodness

    The pulp and the seed are not the same thing. A 2020 laboratory study of jamun pulp and seed[3] separated the two and measured each.

    • Pulp: Reported at 83.51% moisture, with lower protein, lipid and carbohydrate content than the seed
    • Seed: Reported at 62.25% moisture, with 19.96% protein, 2.47% lipids and 14.95% carbohydrates
    • Phenolic compounds: Measured at 22.59 mg GAE per g in the seed against 1.56 mg GAE per g in the pulp
    • Anthocyanins: A study of anthocyanin-enriched jamun extracts[4] found malvidin, petunidin, delphinidin, cyanidin and peonidin in the pulp, and no anthocyanins in the seed

    The same anthocyanin study broke the pulp pigments down by proportion. It found malvidin at 44.4%, petunidin at 24.2%, delphinidin at 20.3%, cyanidin at 6.6% and peonidin at 2.2%. It also reported ellagic acid and ellagitannins at 0.5% in the seed against 0.17% in the pulp.

    A separate study on extracting anthocyanin from jamun pulp[5] reported a total monomeric anthocyanin content of 10.58 mg per 100 g under its optimised extraction conditions. That is an extraction result rather than a food label figure.

    Those numbers come from individual research papers, not from a national food composition table. Standard nutrient values for jamun would need an Indian food composition source.

    What does the evidence say about jamun and blood sugar? 

    Jamun and Blood Sugar

    The picture depends on which part was tested, and on whether the study was in people. The table below sets out what the retrieved sources report.

    What was tested What the evidence says
    Seed powder in people The 2015 review reports that capsuled seed powder given to patients with severe diabetes notably reduced blood glucose levels.
    Leaves in people The same review reports that a single dose of decocted dried leaves had no effect on serum glucose in young people with normal blood glucose.
    Leaves across trials A comprehensive review of guava and jamun leaves[6] reports reductions in fasting blood glucose across trials. It states the level of evidence is low, because of the small number of human studies and limitations including single-centre design, small sample sizes and poor methodological quality.
    Seed extract in animals The 2015 review describes reduced blood and urine glucose in diabetic rats given an ethanolic seed extract. Those are animal results.
    The fruit pulp The pulp research retrieved here is laboratory work on extracts, covering antioxidant and antimicrobial activity rather than blood glucose in people.

    The strongest human signal is for the seed, not for the fruit as it is eaten.

    What the research does not show 

    The clinical evidence is thin. The 2015 review states that very limited data has come from clinical trials, despite the accumulated knowledge on the pharmacological properties of the plant.

    Most of the remaining work is preclinical or laboratory based. The pulp and seed study tested extracts in vitro, and the review of the genus draws mainly on animal models.

    No source retrieved for this article sets an amount of jamun to take, a time of day to take it, or a length of time to continue. Those figures would need a pharmacopoeial or regulatory source.

    Also Read: What Is Shatavari? A Complete Guide to Its Uses and Health Benefits

    What side effects can jamun cause? 

    Use Jamun with Care

    The retrieved sources report little about side effects in people. The 2015 review states that S. cumini did not produce acute or chronic toxicity when given by mouth in the studies it surveyed.

    It describes rodent work in which a hydroalcoholic leaf extract at doses as high as 2 g per kg produced no toxic effects. In the same work, chronic treatment for up to 180 days at 50, 100 and 250 mg per kg caused no haematological, biochemical or histological changes in target organs.

    Those are animal findings. A record of side effects in people was not found in the sources retrieved for this article. Absence of a record is not the same as evidence of safety.

    Who should be careful with jamun? 

    Blood sugar is where the caution sits. The concern is not the fruit at a meal, but concentrated preparations taken alongside treatment.

    Situation What to do
    Taking diabetes medicines The 2015 review reports that seed powder reduced blood glucose in patients with severe diabetes. Anyone already taking glucose-lowering medicine should speak to a doctor before adding jamun preparations.
    Living with diabetes Blood glucose is the outcome most often studied with jamun. A doctor or pharmacist should be involved before it is used alongside prescribed treatment.
    Pregnancy or breastfeeding The sources retrieved for this article do not cover jamun in pregnancy or breastfeeding. That gap is itself a reason to ask a doctor first.
    Children The retrieved sources do not set an amount for children or report studies in them.
    Concentrated products Research used extracts and seed powder rather than the fruit as eaten. A product label and a pharmacist are the right guide for a concentrated preparation.

    If you take regular medicines, ask a pharmacist before adding a jamun preparation to them.

    Can jamun affect diabetes medicines? 

    It may. The 2015 review reports that capsuled seed powder reduced blood glucose in patients with severe diabetes, which is the same direction of effect as a glucose-lowering medicine.

    Where two things push blood glucose the same way, the combination is a question for a prescriber. It is not something to test at home by adding one to the other.

    The retrieved sources do not describe formal interaction studies between jamun and named medicines. That is a gap in the evidence rather than a reassurance.

    Where can you buy jamun products online? 

    Medkart does not sell jamun as a fresh fruit. It lists Ayurvedic preparations, and jamun appears among the ingredients of some of them.

    Ashtamrut SF Diabetes Juice lists jamun, given as Syzygium cumini, among its key ingredients alongside karela, methi and amla. The Ayurvedic products category and the Ayurvedic composition listing show what is stocked. Medkart states that the medicines it sells are sourced from WHO-GMP certified manufacturers.

    Medkart’s medicine comparison tool places products side by side, and the medicines index lists what is in stock. The details a reader can compare include:

    • Active ingredient
    • Strength
    • Dosage form
    • Manufacturer
    • Pack size
    • Current price

    An Ayurvedic preparation taken alongside prescribed treatment should be discussed with a doctor or pharmacist first.

    Key takeaways 

    • Jamun is the fruit of Syzygium cumini, known in English as the Indian blackberry.
    • Traditional use covers the leaves, seeds, fruit and bark, with the seed most associated with diabetes.
    • Laboratory work reports anthocyanins in the pulp and a much higher phenolic content in the seed.
    • Human evidence on blood sugar comes mainly from seed powder and leaves, not from the fruit as it is eaten.
    • A review of guava and jamun leaves rates the level of evidence as low.
    • A 2015 review states that very limited data has come from clinical trials.
    • No source retrieved for this article sets an amount of jamun to take or how long to take it.
    • Anyone taking diabetes medicine should speak to a doctor before adding jamun preparations.

    FAQs: Common Questions About Jamun 

    Q. What else is jamun called? 

    It has several names. The 2015 review gives jamun as the Indian name, black plum as the European one, jambolan in Spanish-speaking countries and jambolão in Brazil. The botanical name is Syzygium cumini, and older papers sometimes use Eugenia jambolana for the same plant.

    Q. Does eating the fruit do the same as the seed powder used in studies? 

    There is no evidence retrieved here that equates the two. The human results in the 2015 review come from capsuled seed powder, which is a concentrated preparation of a different part of the plant. Eating the fruit in season is not the same intervention, and no source retrieved for this article measured it that way.

    Q. Is the seed more active than the pulp? 

    By the laboratory measures used, yes. The study of anthocyanin-enriched extracts reported antioxidant capacity of 3,379 trolox equivalents per gram for the seed against 1,445 for the pulp. The 2020 study found total phenolic compounds far higher in the seed than in the pulp, though both figures come from laboratory assays rather than from people.

    Q. Can jamun replace a diabetes medicine? 

    No. Nothing in the sources retrieved for this article supports using jamun in place of prescribed treatment, and the reviews describe the clinical evidence as limited. A prescribed medicine should only be stopped or changed on the advice of the prescriber.

    Q. Why do laboratory results not always apply to people? 

    Because a compound that acts in a dish or in a rat may behave differently in the body. The reviews retrieved here make that point about jamun directly, describing the human data as very limited and rating the level of evidence as low. That is why the study type matters as much as the finding.

    Q. Is jamun safe to eat as an ordinary fruit? 

    It is eaten as a seasonal fruit across India, and the toxicity work described in the 2015 review found no acute or chronic toxicity by mouth in animals. The retrieved sources do not raise a concern about the fruit as food. Concentrated preparations are a separate question, and one for a pharmacist.

    References 

    Medical disclaimer: This article gives general information only. It does not replace advice from a doctor or pharmacist. No medicine or supplement should be started, stopped or changed without advice from the prescriber or a qualified pharmacist.

  • Ibuprofen: Uses, Dosage, Side Effects and Precautions

    Ibuprofen: Uses, Dosage, Side Effects and Precautions

    Ibuprofen is the generic name of a painkiller that also reduces inflammation. It is a prescription medicine in India, sold under several brand names as tablets and as a liquid.

    Those products are made by different companies. The active ingredient is the same across them, but the strength, pack size and price are not.

    What is ibuprofen? 

     How Ibuprofen Works

     

    Ibuprofen is a non-steroidal anti-inflammatory drug. MedlinePlus[1] explains that it works by stopping the body’s production of a substance that causes pain, fever and inflammation.

    The NHS[2] describes it as a painkiller that also reduces swelling and inflammation. It lists tablets and capsules, gels and sprays, liquid, and granules among the forms sold.

    Its status in India is set by the Drugs Rules, 1945[3]. Ibuprofen appears at entry 244 in Schedule H, the schedule of prescription drugs. Rule 97 requires the pack to carry the symbol Rx and a warning against retail sale without a doctor’s prescription.

    What are the main ibuprofen uses? 

    ibuprofen uses

     

    Ibuprofen is used for pain, fever and inflammation. The NHS names headaches and migraines, joint and muscle pain, pain after an injury, toothache, period pain and a high temperature.

    DailyMed’s prescribing information[4] lists three approved uses for the tablets. They are relief of the signs and symptoms of rheumatoid arthritis and osteoarthritis, relief of mild to moderate pain, and treatment of primary dysmenorrhoea.

    MedlinePlus separates prescription ibuprofen, used for arthritis pain and for mild to moderate pain, from non-prescription ibuprofen, used to reduce fever and relieve minor aches. That split describes United States products. In India ibuprofen sits in Schedule H, so that non-prescription category does not apply.

    Popular brands containing ibuprofen 

    Several ibuprofen brands are sold in India. The company names below are those shown on the Medkart listing for each pack.

    Brand Name Active Ingredient Available Strengths / Forms* Manufacturer / Company
    Brufen 200 Ibuprofen 200 mg tablets Abbott Health Care Private Limited
    Brufen 400 Ibuprofen 400 mg tablets Abbott Health Care Private Limited
    Ibugesic 200 Ibuprofen 200 mg tablets Cipla Pharmaceutical Company Limited
    Ibugesic RTU Ibuprofen oral solution Cipla Pharmaceutical Company Limited
    Ibuprofen Ibuprofen 400 mg tablets Torque Pharmaceuticals Pvt Ltd

    Examples of listed strengths and forms, not a complete catalogue. Product ranges can change.

    Availability and pack size differ between products. The range sold under any one brand can change.

    Ibuprofen composition and available strengths 

    Ibuprofen composition

    Ibuprofen tablets are commonly sold at strengths of 200 mg and 400 mg. NHS guidance on how and when to take ibuprofen[5] describes both strengths as tablets and capsules, alongside gel, spray, liquid and granules.

    DailyMed’s prescribing information describes prescription tablets at 400 mg, 600 mg and 800 mg. Those higher strengths belong to a United States label, not to Indian products.

    A strength such as ibuprofen 400 mg describes the amount of active ingredient in that product. It is product information, not a dosing instruction.

    Medkart’s listings for ibuprofen 400 mg and ibuprofen 200 mg show tablets and an oral solution among the forms stocked.

    Also Read: Ibugesic Plus: Dosage Instructions, Benefits & Side Effects

    How is ibuprofen dosage decided? 

    There is no one dose that applies to every ibuprofen prescription. The condition, the strength and the length of treatment all come into it.

    DailyMed’s prescribing information gives 400 mg every four to six hours as needed for mild to moderate pain. For rheumatoid arthritis and osteoarthritis it gives 1,200 to 3,200 mg a day, with 3,200 mg as the maximum. It also says to use the lowest effective dose for the shortest duration.

    The NHS describes smaller amounts for the pharmacy strengths. It gives one or two 200 mg tablets up to three times a day, or one 400 mg tablet up to three times a day. It also asks for at least four hours between doses.

    Those two sets of figures describe different products in different countries. MedlinePlus advises swallowing the tablet whole rather than chewing or crushing it. What applies to one person is a decision for the prescriber.

    What are the common ibuprofen side effects? 

     ibuprofen side effects

    Stomach upset is the most commonly reported problem. NHS guidance on ibuprofen side effects[6] lists indigestion and stomach aches, feeling sick or being sick, headaches, a rash, dizziness, and diarrhoea or constipation.

    MedlinePlus lists constipation, wind, bloating, dizziness, nervousness and ringing in the ears among its common effects.

    The NHS lists serious effects that need urgent attention, including:

    • Stomach ulcers or bleeding, with tummy pain, vomiting blood, or stools that are black and tar-like
    • Kidney problems, with blood in the urine or swelling of the ankles, feet or hands
    • Shortness of breath or unusual paleness
    • A swollen throat or tongue, a raised itchy rash, or difficulty breathing

    The NHS states that the risk of serious side effects is higher on a high dose, or when ibuprofen is taken for a long time.

    Why the stomach and heart warnings matter 

    Ibuprofen belongs to a drug class that carries two standing warnings. MedlinePlus states that people who take NSAIDs other than aspirin may have a higher risk of a heart attack or a stroke than people who do not take them.

    The same warning says NSAIDs such as ibuprofen may cause ulcers, bleeding, or holes in the oesophagus, stomach or intestine. DailyMed carries both points as a boxed warning, and adds that gastrointestinal bleeding can happen at any time during use and without warning symptoms.

    MedlinePlus notes that the risk is higher with long-term use, higher doses, older age, smoking and drinking alcohol. DailyMed adds that the cardiovascular risk may increase with the duration of use.

    Who should not take ibuprofen? 

    Several groups are told not to take it at all. NHS guidance on who can and cannot take ibuprofen[7] says most adults can use it, and then sets out the situations where it is not suitable.

    Situation What to do
    A past reaction to aspirin or an NSAID The NHS lists a previous allergic reaction to ibuprofen, aspirin or another NSAID among the situations where ibuprofen is not suitable. DailyMed contraindicates it in anyone with a history of asthma, hives or allergic reactions after aspirin or an NSAID.
    A stomach ulcer, now or in the past The NHS lists a current or past stomach ulcer among the situations where ibuprofen is not suitable. DailyMed’s boxed warning covers bleeding, ulceration and perforation of the stomach or intestines.
    Heart, liver or kidney conditions The NHS lists all three among the situations where ibuprofen is not suitable. DailyMed warns that NSAIDs can bring on or worsen high blood pressure, and that long-term use can injure the kidneys.
    Pregnancy or trying to conceive The NHS lists both among the situations where ibuprofen is not suitable. MedlinePlus advises avoiding ibuprofen at around 20 weeks of pregnancy and later.
    Heart bypass surgery DailyMed contraindicates ibuprofen for pain around the time of coronary artery bypass graft surgery.
    Other regular medicines The NHS says to check with a doctor or pharmacist before taking ibuprofen alongside anticoagulants, steroid medicines, antidepressants or blood pressure medicines.

    The NHS also says anyone who is breastfeeding should check with a pharmacist or doctor before using ibuprofen.

    Generic ibuprofen vs brand-name ibuprofen 

    Generic ibuprofen vs brand-name ibuprofen

    Generic and branded ibuprofen contain the same active ingredient. The US FDA[8] states that a generic medicine matches the brand-name medicine on active ingredient, strength, dosage form and route of administration, and is bioequivalent to it.

    The FDA adds that approved generics provide the same clinical benefit and risks as their brand-name counterparts. That is the U.S. FDA standard, and an India-specific regulatory source is needed before making the same claim about an Indian product.

    Products can still differ in manufacturer, inactive ingredients, appearance and price. The same active ingredient and strength alone do not prove that two products are interchangeable. A doctor or pharmacist should confirm any switch between brands.

    Buy or compare ibuprofen tablets on Medkart 

    Medkart sells ibuprofen products online in several brands and pack sizes, including Brufen 400 mg in a pack of 15, and lists them as prescription items. Medkart states that the medicines it sells are sourced from WHO-GMP certified manufacturers.

    Medkart’s medicine comparison tool places products side by side, and the medicines index lists what is in stock. The details a reader can compare include:

    • Active ingredient
    • Strength
    • Dosage form
    • Manufacturer
    • Pack size
    • Current price

    Any suggested alternative should be discussed with a doctor or pharmacist before changing a prescribed medicine.

    Key takeaways 

    • Ibuprofen is a non-steroidal anti-inflammatory drug used for pain, fever and inflammation.
    • Ibuprofen is listed at entry 244 in Schedule H of India’s Drugs Rules, 1945, which makes it a prescription drug.
    • A strength such as ibuprofen 400 mg is product information, not an instruction about how much to take.
    • Indigestion and stomach ache are among the most commonly reported side effects.
    • NSAIDs other than aspirin carry a stated risk of heart attack and stroke.
    • The same class can cause ulcers, bleeding or perforation in the stomach or intestine, sometimes without warning symptoms.
    • The risk of serious effects rises with higher doses, longer use, older age, smoking and alcohol.
    • A past reaction to aspirin or an NSAID, a stomach ulcer and pregnancy are among the reasons ibuprofen is not suitable.

    FAQs: Common Questions About Ibuprofen 

    Q. Can ibuprofen be taken at the same time as paracetamol? 

    For adults, yes. NHS guidance on common questions about ibuprofen[9] says adults can take ibuprofen at the same time as paracetamol if needed. It adds that it is worth trying them separately first, to see whether one alone relieves the pain. That advice covers two different medicines, not two NSAIDs, which the NHS advises against combining.

    Q. How long can ibuprofen be taken for? 

    Not long without advice. The NHS says ibuprofen tablets and capsules should not be taken for more than 10 days unless a doctor advises it. It also says the smallest dose needed should be taken for the shortest time needed. Pain still there after that point is a reason to see a doctor.

    Q. Should ibuprofen be taken with food? 

    Yes. MedlinePlus advises taking ibuprofen with food to prevent stomach upset. The NHS says tablets and capsules should be swallowed with water, ideally with or after food. Neither source presents food as a substitute for the drug class precautions.

    Q. What happens if too much ibuprofen is taken? 

    It can be dangerous. The NHS advises getting advice when more than the recommended amount has been taken, because an ibuprofen overdose can sometimes cause harm. The right step is to contact a doctor, a pharmacist or a hospital straight away rather than waiting to see what develops.

    Q. Can ibuprofen be given to a child? 

    That is a decision for a doctor. MedlinePlus describes non-prescription ibuprofen being given to children and infants every six to eight hours, with no more than four doses in 24 hours. Those directions describe United States products, and the NHS keeps its advice for children on a separate page. In India ibuprofen is a Schedule H medicine, so a prescriber decides whether a child takes it at all.

    Q. Do ibuprofen gels and sprays carry the same risks as the tablets? 

    They are less likely to cause side effects. NHS guidance on ibuprofen side effects says side effects are less likely with the gel or spray than with tablets, capsules, liquid or granules. That is a statement about likelihood, not a claim that the skin preparations carry no risk. A pharmacist can say which form suits a situation.

    References 

    Medical disclaimer: This article provides general information and does not replace advice from a doctor or pharmacist. Ibuprofen is a non-steroidal anti-inflammatory drug listed in Schedule H of India’s Drugs Rules, 1945, so ibuprofen products in India are prescription medicines. Brands with the same composition should only be substituted under the guidance of a healthcare professional or pharmacist because product details and approved indications can differ.

  • Hair Oil Guide: 15 Types, Benefits and How to Choose

    Hair Oil Guide: 15 Types, Benefits and How to Choose

    Oiling hair is one of the few grooming habits almost every Indian household already has. What most of us never got told is which oil does what, or why the order of the steps matters.

    This guide covers fifteen oils, with the steps for each, what it is actually good for, and the one thing about it worth knowing before you start.

    What this article covers 

    • Coconut oil
    • Sesame oil
    • Mustard oil
    • Almond oil
    • Castor oil
    • Olive oil
    • Argan oil
    • Jojoba oil
    • Sunflower oil
    • Bhringraj oil
    • Amla oil
    • Brahmi oil
    • Onion oil
    • Rosemary oil
    • Tea tree oil

    The first nine are plain oils you can buy as a single ingredient. The next four are herbal oils, made by infusing a herb into a base. The last two are essential oils, which are used differently and never neat.

    Why does oiling help hair? 

    oil helps grow hair

    Hair is dead protein once it leaves the follicle, so nothing you put on it repairs it. What oil does is sit on and inside the shaft, reduce friction, and cut the damage that washing and combing cause.

    One oil does measurably more than the others. A 2021 review in the Indian Journal of Plastic Surgery[1] reports that coconut oil was the only oil that reduced protein loss. That held for both damaged and undamaged hair, used before and after washing. Mineral oil and sunflower oil did not.

    The reason is chemistry. The same review credits lauric acid, which has a high affinity for hair protein and a low enough molecular weight to penetrate to the cortex. Bulkier oils stay on the surface.

    What does hair oil do for hair growth? 

    It protects the hair you already have rather than speeding up new growth. Growth happens at the follicle, below the skin, and an oil sitting on the shaft does not reach it.

    What oiling changes is how much of that growth you keep. Cutting breakage means more length stays on your head instead of collecting in the comb.

    So a hair growth routine is really a protective one. Oil before you wash, handle wet hair gently, comb from the ends upwards, and change one thing at a time so you know what made the difference.

    Which hair oil should you choose? 

    Hair Oil Selection

    Match the oil to your hair rather than to the label on the bottle.

    If your hair is What tends to suit it
    Fine or quick to go oily Lighter oils that absorb rather than sit: jojoba, argan, sunflower. A few drops on the mid-lengths and ends, not the scalp.
    Thick, coarse or dry Heavier oils hold up better: coconut, sesame, or castor thinned into a lighter oil.
    Curly or frizz-prone Any of the plain oils, applied to damp hair on the mid-lengths and ends, to seal water in before it escapes.
    Itchy or flaking at the scalp Keep oil light and occasional. Heavy oil on an already irritated scalp usually makes it worse, and a scalp that stays sore needs a doctor.
    Colour-treated or heat-styled Coconut oil before washing, since that is where the protein-loss benefit was measured.
    Prone to matting or tangling Do not leave neat virgin oil on for hours. The same review names plica polonica, a hair matting condition, as a risk of applying virgin oil directly.

    Before you start 

    Check Before Use New Oil

    Try any new oil on a small patch of inner forearm first and leave it for a day. If the skin reacts, do not put it on your scalp.

    Wash off anything that stings, burns or reddens the scalp. That is not the oil working.

    Two cautions apply throughout. Almond oil is a nut product, so skip it entirely if you have a nut allergy rather than patch-testing it. And the two essential oils at the end of the list are never used neat. A 2025 review in Skin Appendage Disorders[2] records allergic contact dermatitis and scalp irritation among reactions reported to topical herbal preparations.

    The Oils – 15 Types 

    All Types of Hair Oil

    1. Coconut oil 

    Coconut oil is pressed from kernel and turns solid below about 24 degrees. It is the oil most Indian kitchens already have.

    How to use it

    1. Warm two to three tablespoons between your palms until it runs clear.
    2. Part your hair and work it into the scalp for two or three minutes.
    3. Draw whatever is left down through the mid-lengths and ends.
    4. Leave it 30 minutes to an hour, then wash out with shampoo.

    Benefits

    • The one common oil measured to cut protein loss from washing
    • Costs very little and is sold in every shop
    • Doubles as a body and cuticle oil

    Good to know: Use it before you wash, not only after. The protein-loss finding covers both, and pre-wash is the half most people skip.

    2. Sesame oil 

    Sesame oil, or til oil, is pressed from sesame seeds. It is the traditional oil for a warm head massage in most of India.

    How to use it

    1. Warm two tablespoons until comfortably warm, never hot.
    2. Massage into the scalp in slow circles for five minutes.
    3. Work the rest through to the ends and leave for an hour, or overnight if your hair is very dry.
    4. Wash out with shampoo. It takes two rounds.

    Benefits

    • Heavier and more warming than coconut oil in winter
    • Cheap and available everywhere in India
    • Good slip for a proper massage

    Good to know: Buy plain sesame oil, not the dark toasted kind used for cooking. Toasted oil has a strong smell that clings to hair for days.

    3. Mustard oil 

    Mustard oil, or sarson ka tel, is pressed from mustard seeds and has a sharp, unmistakable smell.

    How to use it

    1. Warm one to two tablespoons.
    2. Work it into the scalp and hair, using less than you would coconut oil.
    3. Leave for 30 to 45 minutes.
    4. Wash out thoroughly. The smell needs shampoo, not just water.

    Benefits

    • Very inexpensive and widely stocked
    • Thicker than most oils, so a little covers a lot
    • Warms the scalp noticeably in cold weather

    Good to know: The smell is the main reason people give up on it. Mixing it half and half with coconut oil keeps most of the feel and loses some of the pungency.

    4. Almond oil 

    Sweet almond oil is pressed from almonds and is light, mild and almost odourless.

    How to use it

    1. Warm a tablespoon between your palms.
    2. Massage into the scalp, or use a few drops on the ends alone if your hair is fine.
    3. Leave for 30 minutes to an hour.
    4. Wash out as usual.

    Benefits

    • Light enough for fine hair that heavier oils weigh down
    • Mild smell that does not compete with anything
    • Sold in every chemist in India

    Good to know: This is a nut product. If you have a nut allergy, do not use it and do not patch-test it. Jojoba or sunflower oil does the same job without the risk.

    5. Castor oil 

    Castor oil is pressed from castor seeds and is far thicker than any other oil here. It pours like syrup.

    How to use it

    1. Mix one part castor oil into three or four parts coconut, sesame or almond oil.
    2. Warm the blend and work it into the scalp and ends.
    3. Leave for 30 minutes to an hour.
    4. Wash out with shampoo, twice if needed.

    Benefits

    • Acts as a moisturiser and coats the shaft heavily
    • A small bottle lasts a very long time once diluted
    • Adds noticeable weight and shine to fine, flyaway hair

    Good to know: Never use it neat. Undiluted castor oil is difficult to wash out and is the oil most often behind a matted, tangled mess the next morning.

    6. Olive oil 

    Olive oil is the same bottle you cook with, pressed from olives. It is medium weight and slightly green.

    How to use it

    1. Warm two tablespoons.
    2. Apply mostly to the mid-lengths and ends, going light at the roots.
    3. Leave for 30 minutes.
    4. Wash out with shampoo.

    Benefits

    • Already in the kitchen, so nothing to buy
    • Heavier than sunflower, lighter than castor
    • Rinses out more easily than most thick oils

    Good to know: Olive oil sits on the surface rather than penetrating, so it conditions the outside of the hair without doing what coconut oil does inside it.

    Also Read: Mahabringraj Oil: The Natural Solution for Healthy Hair Growth

    7. Argan oil 

    Argan oil is pressed from the kernels of a Moroccan tree. It is light, quick to absorb and sold in small bottles.

    How to use it

    1. Put two or three drops on your fingertips.
    2. Rub your palms together and smooth it over damp mid-lengths and ends.
    3. Leave it in. There is nothing to wash out.

    Benefits

    • Absorbs fast enough to use on hair you are about to leave the house with
    • Almost no smell
    • A 30 ml bottle lasts months at three drops a time

    Good to know: The 2021 review notes argan oil contains antioxidants but lacks scientific evidence for its conditioning claims. It is pleasant and convenient; the marketing runs ahead of the data.

    8. Jojoba oil 

    Jojoba is technically a liquid wax, pressed from the seeds of a desert shrub. It feels closer to the scalp’s own oil than anything else here.

    How to use it

    1. Warm three or four drops in your palm.
    2. Work into the scalp if it feels tight, or through the ends if they feel rough.
    3. Leave it in, or wash out after an hour if you prefer.

    Benefits

    • Light enough for oily hair and fine hair
    • Keeps far longer than seed oils without turning
    • Thins out heavier oils that feel like too much alone

    Good to know: Because it is a wax rather than an oil, an open bottle is still fine a year later. Almond and sunflower oil are not.

    9. Sunflower oil 

    Plain sunflower oil, pressed from the seeds. It is one of the lightest cooking oils and very cheap.

    How to use it

    1. Warm a tablespoon.
    2. Apply to the scalp and hair, or use it as the base you dilute castor oil into.
    3. Leave for 30 minutes.
    4. Wash out with shampoo.

    Benefits

    • Extremely cheap and in most kitchens
    • Light and easy to wash out
    • Useful as a carrier for heavier oils and essential oils

    Good to know: The 2021 review found sunflower oil did not reduce protein loss, and put that down to its bulky molecular structure. It conditions the surface but does not get inside the shaft.

    10. Bhringraj oil 

    Bhringraj oil is made by infusing the herb Eclipta alba into a base oil, usually coconut or sesame. It is dark green and smells strongly herbal.

    How to use it

    1. Warm two tablespoons.
    2. Section your hair and apply along the scalp, then through the lengths.
    3. Massage for five minutes and leave for at least an hour.
    4. Wash out with shampoo.

    Benefits

    • The classic Ayurvedic hair oil, easy to find in any Indian shop
    • Comes ready-blended, so nothing to mix
    • Strong herbal smell that some people genuinely like

    Good to know: What you are buying is mostly the base oil. Check whether the base is coconut or a mineral oil, because that changes how it behaves more than the herb does.

    11. Amla oil 

    Amla oil is Indian gooseberry infused into a base oil. It is one of the oldest hair preparations in India and usually comes dark and thick.

    How to use it

    1. Warm one to two tablespoons.
    2. Work it into the scalp and along the hair.
    3. Leave for an hour, or overnight with a towel on the pillow.
    4. Wash out with shampoo.

    Benefits

    • Widely sold and inexpensive
    • Heavier feel that suits coarse hair
    • Traditional choice for a weekly oiling routine

    Good to know: Many commercial amla oils are mineral oil with amla extract and colour added. Mineral oil does not penetrate hair, so read the base before you judge the oil.

    12. Brahmi oil 

    Brahmi oil infuses Bacopa monnieri into a base oil. It is usually lighter than bhringraj and less strongly scented.

    How to use it

    1. Warm a tablespoon or two.
    2. Apply to the scalp with fingertips and massage for a few minutes.
    3. Leave for 45 minutes to an hour.
    4. Wash out as usual.

    Benefits

    • Lighter than most Ayurvedic oils, so easier on fine hair
    • Milder smell than bhringraj or mustard
    • Often sold blended with bhringraj and amla in one bottle

    Good to know: Brahmi is sometimes confused with gotu kola, a different plant sold under similar names. Check for Bacopa monnieri on the label if it matters to you.

    13. Onion oil 

    Onion oil is red onion extract carried in a base oil. It became popular in India in the last few years and is now sold everywhere.

    How to use it

    1. Apply one to two tablespoons to the scalp with an applicator bottle or fingertips.
    2. Massage for three to five minutes.
    3. Leave for 30 minutes to an hour, no longer.
    4. Wash out with shampoo. It usually takes two rounds.

    Benefits

    • Comes ready-made, so no chopping or straining
    • Light enough for most hair types
    • Widely stocked and often blended with amla or bhringraj

    Good to know: The smell is the honest drawback. The 2025 review lists unpleasant odour as the main reported problem with onion preparations, and the reason people stop using them.

    14. Rosemary oil 

    Rosemary oil is an essential oil, steam-distilled from the herb. It is highly concentrated and is never applied neat.

    How to use it

    1. Add three to five drops to one tablespoon of coconut, jojoba or sunflower oil.
    2. Stir, then work the blend into the scalp only.
    3. Leave for 30 minutes.
    4. Wash out with shampoo.

    Benefits

    • A few drops go a long way, so one bottle lasts
    • Sharp, clean smell that most people prefer to herbal oils
    • Mixes into any plain oil you already own

    Good to know: Neat essential oil on the scalp can cause a reaction even in people who tolerate it diluted. Dilute it every time, and keep it away from your eyes.

    15. Tea tree oil 

    Tea tree oil is an essential oil distilled from the leaves of an Australian shrub. Like rosemary, it is used in drops rather than spoonfuls.

    How to use it

    1. Add two to three drops to one tablespoon of a carrier oil.
    2. Apply to the scalp, not through the lengths.
    3. Leave for 20 to 30 minutes.
    4. Wash out with shampoo.

    Benefits

    • Very small quantities needed, so a bottle lasts months
    • Distinct medicinal smell that fades after washing
    • Blends into any of the plain oils above

    Good to know: Tea tree oil is not put on the scalp neat under any circumstances. If the scalp is already broken, sore or weeping, leave it alone entirely and see a doctor.

    What to expect, and how long it takes 

    Hair Grooming With Oil

    Oiling is grooming, not repair. It reduces the damage washing and combing do, and it makes hair easier to handle. It does not rebuild a damaged shaft, because hair is not living tissue.

    Give any routine six to eight weeks before you judge it, and judge it on how the hair feels and behaves rather than on length. A week tells you nothing.

    What would count as it not working? A scalp that itches or flakes more than before, hair that mats or tangles worse, or spots that stay sore. Any of those means stop, not persist.

    When is oiling not enough? 

    Consult With Doctor for Hair care

    Oils work slowly where they work at all, and they suit upkeep rather than repair.

    Hair that is falling out suddenly, coming out in patches, or thinning fast is a reason to see a doctor rather than to try the next oil. So is a scalp that is painful, weeping, bleeding or not settling. The 2025 review is explicit that people should discuss herbal preparations with a healthcare professional rather than assume they are a substitute.

    If you want something more consistent than a kitchen blend, a formulated hair oil is a fair alternative. It is made to the same recipe every time and carries its own label, which a mix poured by hand does not.

    Where can you buy hair oil on Medkart? 

    Medkart lists hair oils alongside its medicine range. The personal care category covers hair oils, cleansers and other topical preparations.

    Hair oils listed on Medkart include:

    Medkart states that the medicines it sells are sourced from WHO-GMP certified manufacturers. Its comparison tool places products side by side, and the medicines index lists what is in stock.

    If you already use a prescribed scalp treatment, ask a pharmacist before adding an oil on top of it.

    Key takeaways 

    • Hair is dead protein, so oil reduces damage rather than repairing it.
    • Coconut oil is the one common oil measured to cut protein loss from washing.
    • Lighter oils suit fine or oily hair, heavier oils suit thick or dry hair.
    • Castor oil is always diluted into a lighter oil, never used neat.
    • Almond oil is a nut product and is skipped entirely by anyone with a nut allergy.
    • Rosemary and tea tree are essential oils and are used in drops, always diluted.
    • Many commercial herbal oils are mineral oil with extract added, so read the base.
    • Sudden, patchy or fast hair loss needs a doctor rather than another oil.

    FAQs: Common Questions About Hair Oiling 

    Q. How often should you oil your hair? 

    Once or twice a week suits most people. Fine or quickly oily hair often does better with once a week on the ends only, while coarse or dry hair can take twice. If your scalp feels heavy, itchy or spotty after a few weeks, you are oiling too often or using too much.

    Q. Should oil go on wet hair or dry hair? 

    Both work, for different reasons. On damp hair, oil helps seal water in, which is why curly hair usually does better that way. On dry hair before a wash, it coats the shaft and takes some of the damage that shampoo would otherwise do.

    Q. Is leaving oil in overnight better? 

    Not necessarily, and for some hair it is worse. An hour is enough for most oils to do what they are going to do. Long overnight sessions with a thick or neat oil are also where matting and tangling most often start.

    Q. Can you mix two oils together? 

    Yes, and it is often the best way to use the difficult ones. Castor oil is far easier diluted, and essential oils have to be. Keep a blend to two or three oils so you know what to drop if your scalp reacts.

    Q. How do you get oil out of hair properly? 

    Shampoo dry hair before wetting it, which sounds wrong and works far better. Work the shampoo into the oiled hair first, then add water and lather. Heavier oils usually need a second round.

    Q. Can oiling make hair look thicker? 

    Only in how it looks, not in how much hair there is. A light oil through the mid-lengths smooths the surface and catches the light, which makes fine hair read as denser in the mirror. It does not change the number of follicles, and too heavy an oil does the opposite and leaves hair looking flat.

    Q. Does a hair care routine need more than oiling? 

    Yes, and the rest of it matters as much. Washing, drying and combing all decide how much hair survives the week, and no oil undoes rough handling on soaking wet hair. A wide-toothed comb and blotting with a towel rather than rubbing are the cheapest parts of the routine.

    References 

    • https://pmc.ncbi.nlm.nih.gov/articles/PMC8719955/
    • https://pmc.ncbi.nlm.nih.gov/articles/PMC12324729/

    Medical disclaimer: This article describes hair oils and oiling practices in common household use. It is written for general interest and does not replace advice from a doctor or pharmacist. A scalp that is painful, spreading or not settling, or hair loss that is sudden or patchy, should be seen by a doctor rather than treated at home, and no medicine should be started, stopped or changed without advice from the prescriber or a qualified pharmacist.

  • Gond Katira: Benefits, Uses, Side Effects and How to Take It

    Gond Katira: Benefits, Uses, Side Effects and How to Take It

    Gond katira is a dried gum that seeps from the stems of certain trees and shrubs, hardens into pale lumps, and swells a great deal when it meets water. It is sold loose in Indian shops and used to thicken food.

    The name causes more trouble than the gum does. Indian food standards recognise two different exuded gums with overlapping common names, different botanical sources and different identity numbers. Which one sits in a given packet is a question only the label can answer.

    What is gond katira? 

    A dried gum exuded from a tree or shrub. Which one depends on the pack, because Indian food standards[1] specify each of the two separately.

    • Tragacanth gum, INS 413: the dried gummy exudation of Astragalus strobiliferus or other species of Astragalus, family Leguminosae. The standard describes translucent, horny pieces 0.5 to 2.5 mm thick, white to pale yellow, odourless, with an insipid mucilaginous taste.
    • Gum karaya, INS 416: the dried gummy exudation from the stems and branches of Sterculia urens and Sterculia villosa, family Sterculiaceae. The standard lists its common names as karaya, gum karaya, sterculia, gum sterculia, kadaya, katilo, kullo and kuterra.

    The two come from different places. The EFSA panel that re-evaluated tragacanth[2] records its collection in Iran, Syria, Turkey and southwest Asia. The panel that re-evaluated karaya gum[3] records that Sterculia urens grows widely throughout the Indian subcontinent.

    Among the requirements tragacanth gum must meet is a karaya gum test.

    No source retrieved for this article establishes which of the two a packet labelled gond katira holds. The botanical name on the pack settles it.

    What are the benefits and uses of gond katira? 

    gond katira benefits and uses

    Both gums do two jobs: they thicken food and add bulk to stool.

    Use What the evidence says
    Constipation The patient leaflet for a licensed sterculia medicine[4] describes the gum as a dietary fibre that relieves constipation. EFSA records bulk-forming laxative use of karaya gum at up to 12 g a day for adults.
    A high-fibre diet The same leaflet lists use by people who need a high fibre diet, for example in diverticular disease of the colon, and by people with a colostomy or an ileostomy.
    After rectal or anal surgery The leaflet lists this use, alongside use by someone who has swallowed something sharp, to reduce the chance of damage to the gut.
    Thickening and stabilising food Both EFSA opinions describe these gums as food additives used to thicken and stabilise.
    Cooling the body in summer No source retrieved for this article tests this use, which is the most common reason the gum is bought in India.

    What is the nutritional value of gond katira? 

    Very little, and that is rather the point. Both gums are large carbohydrate molecules that mostly pass through.

    EFSA states that karaya gum is practically undigested, is not fermented by gut bacteria, and is most probably not absorbed unchanged in humans. It describes tragacanth as unlikely to be absorbed intact.

    On composition, the tragacanth opinion puts protein at about 2 per cent, within a range of 0.5 to 3.4 per cent. Its sugar units vary widely between species, with arabinose from 1 to 51 per cent and galacturonic acid from 9 to 37 per cent.

    A full nutrient profile is missing. No Indian food composition source and no United States FoodData Central entry could be retrieved for gond katira, so figures for energy, fat or vitamins are not given here.

    How do you use gond katira? 

    How do you use gond katira

    With plenty of liquid, and never dry. The licensed sterculia product’s leaflet is the clearest retrieved instruction.

    It says the dry granules are placed on the tongue from the sachet, a spoon or the hand, or sprinkled onto soft food such as yoghurt. They are swallowed with plenty of water or a cool drink, and never chewed or crushed. They are taken after meals, and not just before bed or while lying down.

    The reason sits in the swelling. EFSA records that karaya gum absorbs water and swells to more than 60 times its original volume, increasing about tenfold within the first hour. The NHS[5] advises drinking plenty of fluids with any bulk-forming laxative.

    No retrieved source describes soaking loose gum overnight and drinking it, which is the preparation gond katira is best known for in India.

    Also Read: Top 10 High Fiber Rich Foods for Better Digestion, Weight Loss & Overall Health

    What is the recommended dosage of gond katira? 

    There is no published dose for loose gum. What exists is a dose for a licensed product built on the same gum.

    The leaflet gives adults and the elderly 1 to 2 sachets, or 1 to 2 heaped 5 ml spoonfuls, once or twice a day after meals. That product is 62 per cent sterculia by weight, so the figure describes the granules rather than pure gum.

    Tolerance studies give a sense of scale rather than a dose. EFSA reports 9,900 mg of tragacanth daily for 21 days without adverse effects in five volunteers. For karaya gum it reports 7,000 to 10,500 mg daily tolerated by most people. Abdominal discomfort appeared in seven of 89 volunteers taking 7,000 mg a day for four weeks.

    A weight printed on a bag of gum is product information, not an instruction about how much to take.

    How long can you take gond katira? 

    Not long without checking. The sterculia leaflet says that if the product has not worked after four days, it should be stopped and a doctor or pharmacist seen.

    Anyone who does not feel better, or who feels worse, after four days is told to talk to a doctor.

    No retrieved source sets a duration for loose gum eaten as a food.

    What side effects can gond katira cause? 

     gond katira side effects

    Wind, bloating and stomach pain are the ordinary ones. The sterculia leaflet lists a swollen stomach, flatulence, diarrhoea, nausea and abdominal pain.

    Two entries on the same list are more serious. Blocked intestine and blocked oesophagus both appear on it.

    Allergic reactions are listed as well. Skin rash, itching and nettle rash appear, along with swollen hands, feet or ankles. The most serious is difficulty breathing or swelling of the face, lips, tongue or throat, which calls for stopping at once and telling a doctor.

    EFSA notes case reports of hypersensitivity to tragacanth, possibly linked to its protein content, and very few reports of allergy to karaya gum.

    Who should be careful with gond katira? 

    Anything that already narrows or slows the gut is the main concern. Six situations call for care.

    Situation What to do
    A known blockage in the gut The sterculia leaflet contraindicates the product in anyone told they have an intestinal blockage, faecal impaction, or total loss of muscle tone in the colon.
    Ulcerative colitis The leaflet says a doctor should be spoken to before the product is taken.
    Difficulty swallowing The gum swells rapidly and the leaflet warns that the gullet can block. It should not be taken lying down or at bedtime.
    Children The leaflet does not recommend it under 6 years, and allows 6 to 12 years only on a doctor’s instruction.
    A low-salt diet or an intolerance to some sugars The licensed granules carry 28.7 mg of sodium per 7 g sachet and contain sucrose. Other products will differ, so the pack should be read.
    Regular prescribed medicines The leaflet asks that a doctor or pharmacist be told about any other medicines being taken, including those bought without a prescription.

    On pregnancy the leaflet is reassuring but not blanket. The product can be taken while pregnant or breastfeeding, it says, and a doctor or pharmacist should be asked first.

    Where can you buy gond katira or isabgol online? 

    Gond katira is sold as a food gum rather than as a pharmacy medicine, and Medkart does not list it under that name. The bulk-forming fibre it does list is isabgol.

    Husky Isabgol Powder from Karnataka Antibiotics and Pharmaceuticals and Laxmi Isabgol Powder from Giriraj Enterprise are plain husk powders. Naturolax A from Piramal and Softovac SF from Lupin are combination powders built on isabgol husk.

    These are different substances from gond katira, with their own labels and cautions. Sharing a bulk-forming action does not make two products interchangeable.

    The ispaghula husk composition listing, the Ayurvedic products category and the Ayurvedic composition page show what is stocked. Availability, pack size and price differ between products and can change.

    Medkart states that the medicines it sells are sourced from WHO-GMP certified manufacturers. Medkart’s medicine comparison tool sets products side by side, and the medicines index and search page show current stock. Points worth comparing on a fibre pack:

    • Botanical name of the source plant
    • Whether it is a single gum or a combination
    • Amount per dose
    • Manufacturer
    • Pack size

    Anyone taking regular medicines should speak to a doctor or pharmacist before adding a fibre supplement.

    Key takeaways 

    • Indian food standards recognise two distinct gums with overlapping names, tragacanth as INS 413 and gum karaya as INS 416.
    • Tragacanth comes from Astragalus species in west Asia, while gum karaya comes from Sterculia urens, which grows across the Indian subcontinent.
    • The Indian standard for tragacanth gum includes a karaya gum test among its requirements.
    • Both gums are largely undigested and unabsorbed, so they add bulk rather than nutrients.
    • The clearest retrieved instructions come from a licensed sterculia medicine, not from loose gum.
    • That leaflet gives adults 1 to 2 sachets or 1 to 2 heaped 5 ml spoonfuls, once or twice daily after meals.
    • The gum is taken with plenty of fluid, never dry and never lying down, because the gullet can block.
    • No retrieved source tests the summer cooling use, which is the most common reason the gum is bought in India.

    FAQs: Common Questions About Gond Katira 

    Q. Is gond katira the same as gum ghatti or the other Indian gums? 

    No. The Indian standards set out several exuded gums side by side, each with its own botanical source and identity number. Gum ghatti from Anogeissus latifolia is listed separately, and the shared word gond simply means gum. Two gums that both soften into a jelly can still come from unrelated plants.

    Q. What happens if the gum is swallowed without enough water? 

    The gullet can block. The gum draws in water and expands, and if that happens before it has reached the stomach, it expands in the wrong place. The sterculia leaflet names this outcome twice: once for taking too much, once for taking too little fluid with it.

    Q. How long does a bulk-forming fibre take to work? 

    Longer than most people expect. The NHS says bulk-forming laxatives take up to three days, which is why raising the amount after one disappointing day tends to cause trouble rather than relief. Anything still not working after a few days is a reason to ask a pharmacist.

    Q. Do the two gums behave the same way in the gut? 

    Not quite. EFSA describes karaya gum as practically undigested and not fermented by gut bacteria, so it passes through largely untouched. Tragacanth is partially fermented by gut bacteria, which produces short-chain fatty acids along the way. Both add bulk rather than nourishment.

    Q. Why do stools sometimes look paler after taking a sterculia product? 

    This one is expected. The leaflet notes that it is not unusual for stools to look paler than normal. It puts this down to local contact with the sterculia itself, and says it does not indicate anything untoward. Pale stools that persist after the product is stopped are a different matter and should be mentioned to a doctor.

    Q. Is tragacanth allowed in food outside India? 

    Yes. United States federal regulations[6] affirm gum tragacanth as generally recognised as safe in food, taken from species of Astragalus, with maximum levels set by food category. Those run from 1.3 per cent in fats and oils down to 0.1 per cent in all other foods. That is a United States standard, and an Indian source is needed to make the same claim here.

    References 

    Medical disclaimer: This article gives general information only. It does not replace advice from a doctor or pharmacist. No medicine or supplement should be started, stopped or changed without advice from the prescriber or a qualified pharmacist.

  • Glycerine for Skin: Benefits, Uses, Side Effects and How to Apply It

    Glycerine for Skin: Benefits, Uses, Side Effects and How to Apply It

    Glycerine is a clear, thick liquid used in moisturisers, lotions, soaps and some medicines. It is also called glycerol, and the two names describe the same substance. On skin it acts as a humectant, a type of ingredient that draws in and holds water.

    It is sold in India both as a plain liquid in a bottle and as one ingredient among several in creams and lotions. The strength printed on a pack matters, because what a product does to skin depends on how much glycerine it contains.

    Is glycerine good for skin, and what are its benefits? 

     Glycerine Benefits For Skin

    Yes, mainly for holding water in the outer layer and protecting skin that is dry, chapped or cracked.

    The U.S. FDA’s final order for skin protectant drug products[1] recognises glycerin as a skin protectant active ingredient. Products in that category may state that they temporarily protect minor cuts, scrapes and burns. They may also state that they help prevent and temporarily protect chapped or cracked skin.

    A 2020 review of nonprescription moisturisers[2] describes humectants such as glycerin as hydrating skin by attracting and binding water.

    Use What the evidence says
    Dry skin in atopic dermatitis A 2025 review of emollient studies[3] reports that a 20% glycerol cream, applied twice daily for four weeks by 24 people with atopic dermatitis, raised skin capacitance and lowered water loss through the skin compared with its vehicle.
    Very dry skin in dialysis patients A phase 3 trial[4] of a cream containing glycerol 15% and paraffin 10% recorded a response in 60.2% of 235 patients with moderate to severe uraemic xerosis, against 41.0% on the vehicle.
    Hand dermatitis from wet work In a crossover trial in 32 fabric workers[5], a cream containing 20% glycerin applied twice daily for two weeks lowered hand eczema severity and water loss by about 20%, and raised skin capacitance by about 20%.
    Chapped or cracked skin Labelling for a glycerin 40% ointment on DailyMed[6] states that the product helps prevent and temporarily protects chafed, chapped or cracked skin and lips.
    Facial skin A double-blind split-face trial[7] in 31 women aged 55 to 75 applied a 20% glycerol emulsion twice daily for four months. Hydration measured at the crow’s feet rose further than on the placebo side, while the two sides did not differ significantly on wrinkle visibility.

    The 2020 review excluded studies of single ingredients such as glycerol. Most of the evidence above therefore describes tested formulations rather than plain glycerine.

    How much glycerine is used on the skin? 

    glycerine concentration on skin

    There is no single amount that applies to every use of glycerine on skin.

    The FDA order sets a concentration range rather than a dose. It lists glycerin at 20% to 45% for products sold as skin protectants.

    A figure such as glycerin 20% describes how much glycerine is in that product. It is product information, not an instruction about how much to apply.

    Individual labels sit at different points in that range. DailyMed lists a glycerin 20% gel[8] alongside the glycerin 40% ointment.

    Neither label gives a measured quantity. The gel label says to apply liberally as often as necessary. The ointment label says to apply as needed.

    How do you apply glycerine on the face and body? 

    How do you apply glycerine

    Moisturising products are generally applied to skin that has just been washed and dried.

    The NHS[9] advises applying an emollient as soon as the skin has been patted dry, so that it is absorbed properly. It also advises smoothing the product on rather than rubbing it in, following the direction of hair growth. That helps stop hair follicles becoming blocked.

    The NHS also says it is especially important to apply an emollient to the hands and face, because they are more exposed than the rest of the body.

    The NHS says emollients can be applied as often as a person likes. It suggests at least three or four times a day.

    That page describes emollients as a group and does not name glycerol.

    How long can glycerine be used? 

    That depends on whether the product is a cosmetic moisturiser or a skin protectant.

    The FDA order carries a warning that a doctor should be seen if the condition lasts more than seven days. The glycerin 40% ointment label repeats that boundary. It tells users to stop and ask a doctor if the condition worsens, or if symptoms clear up and return within a few days.

    The glycerin 20% gel label sets a longer boundary. It advises discontinuing use if the condition worsens or does not improve within 10 to 14 days.

    The two labels set different limits. The limit printed on the pack in hand is the one that applies to it.

    Also Read: Best Skincare Products & Routine for Sensitive Skin

    What side effects can glycerine cause? 

    Glycerine side effects

    Glycerine is generally well tolerated on skin, and the side effects reported in trials were local ones.

    The phase 3 trial of the glycerol and paraffin cream recorded irritation or erythema in 2.1% of patients. Worsened itching affected 1.3%, and blisters at the site of application 0.9%. The crossover trial in fabric workers reported no adverse effects among its 32 participants.

    Both glycerin labels on DailyMed are marked for external use only.

    Why glycerine is kept away from the eyes 

    Both DailyMed glycerin labels carry an eye warning. The glycerin 40% ointment label states that the product should not get into the eyes. The gel label advises avoiding contact with them.

    Both labels also direct anyone who swallows the product to get medical help or contact a poison control centre.

    Who should be careful with glycerine? 

     glycerine who should not used

    Very young children, deep wounds and serious burns are the situations these labels single out.

    Situation What to do
    Babies under six months The FDA order requires skin protectant products containing glycerin to carry a statement that a doctor should be asked before use in children under six months. The glycerin 40% ointment label carries the same line.
    Deep or puncture wounds and animal bites Both DailyMed glycerin labels state that the product should not be used on deep or puncture wounds, or on animal bites.
    Serious burns The glycerin 40% ointment label states that it should not be used on serious burns.
    Wound care The glycerin 20% gel label lists stasis ulcers, pressure ulcers, first and second degree burns and post-operative incisions among its uses, and sets a review point at 10 to 14 days.

    If you are using glycerine on skin that is broken or not healing, ask a doctor or pharmacist which product is appropriate.

    Does glycerine appear in medicines as well as cosmetics? 

    Yes. Glycerol is also used as an excipient in medicines.

    The EMA’s annex on excipients in labelling[10] lists glycerol, also written as E422, by route of administration. For an oral medicine the threshold is 10 g per dose. Above that, the leaflet states that glycerol may cause headache, stomach upset and diarrhoea.

    For a rectal medicine the threshold is 1 g, with a note that glycerol may have a mild laxative effect.

    That annex covers glycerol swallowed or given rectally. It carries no cutaneous entry, so it says nothing about glycerine applied to skin.

    Glycerine in Indian cosmetic and drug rules 

    Most glycerine products sold for skin in India are regulated as cosmetics rather than as medicines.

    CDSCO[11] gives the definition of a cosmetic under the Drugs and Cosmetics Act, 1940. It covers anything applied to the human body for cleansing, beautifying, promoting attractiveness or altering the appearance.

    Manufacture is licensed by State Licensing Authorities, and imports are registered by the Central Licensing Authority under the Cosmetics Rules, 2020.

    The 20% to 45% range quoted earlier describes a U.S. standard. No Indian regulatory source setting a permitted glycerine concentration for skin was retrieved, so it should not be read as an Indian requirement.

    Where can you buy glycerine online? 

    Medkart lists glycerine as a plain liquid and inside moisturising creams and lotions.

    Plain glycerine appears in small packs such as Glycerin 50 GM, in larger bottles such as Glycerin 400 ML, and under the glycerol name as Glycerol Liq 200 ML.

    Cream and lotion products include Glicerina Cream from Atopic Laboratories, Aquasoft Cream from Ajanta Pharma and Secalia Lotion from Micro Labs. Availability and pack size differ between products and can change.

    Products sharing the Glycerin 15% w/w composition are grouped on one page. Medkart’s medicine comparison tools line up alternatives on:

    • Active ingredient
    • Strength
    • Dosage form
    • Manufacturer
    • Pack size
    • Current price

    The wider personal care range and the full medicines catalogue carry other moisturising products, and Medkart branches can be found through the store locator. Medkart highlights WHO-GMP certified manufacturers for the medicines it lists.

    If you are not sure which product suits your skin, ask a pharmacist before buying.

    Key takeaways 

    • Glycerine and glycerol are two names for the same substance, used on skin as a humectant.
    • The U.S. FDA recognises glycerin as a skin protectant active ingredient at 20% to 45%.
    • A percentage on a pack describes what the product contains and is not an instruction about how much to apply.
    • Trials of creams containing 15% to 20% glycerol reported better skin hydration and less water loss through the skin.
    • The NHS advises applying an emollient to skin that has just been patted dry, and smoothing it on rather than rubbing it in.
    • Side effects reported in trials were local, and included irritation, redness and worsened itching in a small share of patients.
    • Skin protectant labels containing glycerin tell users to ask a doctor before use in children under six months.
    • Most glycerine skin products sold in India are regulated as cosmetics under the Cosmetics Rules, 2020.

    FAQs 

    Q. Does glycerine remove tan? 

    No retrieved source supports that. The permitted claims for a glycerin skin protectant cover protecting chapped or cracked skin rather than skin tone. The trials described above measured hydration and water loss rather than pigmentation. Anyone concerned about a change in skin colour should raise it with a doctor.

    Q. How soon does glycerine make a difference to dry skin? 

    The trials measured change over weeks rather than days. The fabric workers applied their cream twice daily for two weeks before hydration and water loss were reassessed. The atopic dermatitis cream ran twice daily for four weeks, and the dialysis trial measured its main result after 28 days. None of these trials reported the effect of a single application.

    Q. Does a higher percentage of glycerine work better? 

    The retrieved trials do not answer that. They tested glycerol at 15% and at 20%, while the FDA range for skin protectants runs up to 45%. No retrieved study compared two concentrations against each other in the same participants. A higher figure on a pack cannot be read as a better result.

    Q. Is glycerine better than urea for dry skin? 

    It depends on the measure. The 2025 review reports one trial in 109 people with atopic dermatitis where urea cream produced lower water loss through the skin than the glycerine cream. In a second trial in 197 people, improvement in dryness was similar between the two, and glycerine caused less smarting.

    Q. How long has glycerine been tested for continuous use? 

    Two of the retrieved trials ran for about four months, one in dialysis patients and one on facial skin. Both are far longer than the review points printed on skin protectant labels, which are set for a specific complaint rather than for daily moisturising.

    Q. Does glycerine need to be diluted before use on skin? 

    No retrieved source describes a dilution for use at home. The products covered by the FDA standard and by the trials above contained glycerine within a finished cream, gel or ointment. None of them used the neat liquid. A pharmacist can say how a particular pack of plain glycerine is meant to be used.

    References 

    Medical disclaimer: This article gives general information only. It does not replace advice from a doctor or pharmacist. No medicine or supplement should be started, stopped or changed without advice from the prescriber or a qualified pharmacist.

  • Giloy (Guduchi): Benefits, Uses, Side Effects and Safety

    Giloy (Guduchi): Benefits, Uses, Side Effects and Safety

    Giloy is the common name for Tinospora cordifolia, a climbing shrub used in Ayurveda under the name Guduchi.

    Its use rose sharply during the COVID-19 pandemic. So did a set of published reports linking it to liver injury.

    What is giloy? 

    Giloy

    Giloy is Tinospora cordifolia, a plant of the Menispermaceae family. A 2023 review in the Chinese Journal of Integrative Medicine[1] describes it as a herbaceous vine, or climbing deciduous shrub.

    LiverTox[2], the United States National Institutes of Health database on drug-induced liver injury, records that extracts of the leaves, roots and bark are used.

    LiverTox names more than 60 compounds in Tinospora species, including lactones, steroids, flavonoids, lignans, alkaloids and the characteristic clerodane-type furanoditerpenoids. It identifies the clerodane diterpenoids as the probable cause of the liver injury set out below.

    What is the nutritional value of giloy? 

    Giloy is taken as a herb rather than eaten as a food, so nutrient figures describe the dried plant rather than a dose.

    A 2024 review of giloy leaves[3] gives about 5.2 g of protein and about 52 g of fibre per 100 g of dehydrated leaves. It lists calcium and iron among the minerals present. A 2023 review of the stem in food[4] reports protein and dietary fibre, with vitamin C, calcium and iron in small concentrations.

    Both sets of figures are per 100 g, and a typical daily dose is a small fraction of that weight. No Indian food composition entry for giloy could be retrieved for this article.

    What are the benefits and uses of giloy? 

    Giloy benefits and uses

    Giloy has a long list of traditional uses and a much shorter list of tested ones. The 2023 review lists fevers, jaundice, diabetes, dysentery, urinary infections and skin diseases among its traditional applications.

    The same review names anti-diabetic, immune-modulatory, antiviral, antioxidant and hepatoprotective effects among the pharmacological properties studied. The stem, the leaf and the root are all used.

    LiverTox records a similar list. It names diabetes, rheumatism, jaundice, malaria, asthma, depression, pain and urinary tract infections, with recent use aimed at COVID-19.

    What does the clinical evidence show? 

    Less than the traditional list suggests. The 2023 review states that large-scale clinical studies are still needed.

    Use What the evidence says
    Immune effects in HIV A randomised, double-blind, placebo-controlled trial[5] gave 300 mg three times daily for six months to 68 people. Sixty per cent on the extract reported fewer symptoms against 20 per cent on placebo, but CD4 count did not improve in either group.
    The wider pharmacology The 2023 review reports anti-diabetic, antiviral and immune-modulatory activity from laboratory and animal work, and calls for large-scale clinical studies to establish efficacy in people.
    Giloy leaves The 2024 review of giloy leaves reports that leaf extracts stimulate immune cells including natural killer cells, B cells and T cells. It states that these findings come from laboratory and animal work, and reports no human trials of leaf-based products.
    Everyday immunity No source retrieved for this article establishes that giloy prevents or shortens an ordinary infection in a healthy adult.

    The trial authors add two caveats of their own. Six months may not have been long enough to judge, and not all the objective measures backed up what patients reported.

    How do you use giloy, and how much? 

    Common Forms of Giloy

    Giloy is used as tablets, capsules, powders and juices, and no one dose applies to everyone. LiverTox records a typical dose of 400 to 1,000 mg daily across the forms sold over the counter, which include solutions, powders, capsules and tablets.

    The HIV trial used 900 mg a day, under supervision and with monitoring.

    A strength printed on a pack describes the amount of extract in that product. It is product information, not an instruction about how much to take. What suits a particular person is a question for a doctor or a qualified Ayurvedic practitioner.

    When should you take giloy, and for how long? 

    No source retrieved for this article gives a time of day. The Ministry of AYUSH publishes a technical dossier on Guduchi, and neither that document nor the Ministry’s press statements could be opened while researching this article.

    On duration there is more to go on. The HIV trial ran for six months under medical supervision. LiverTox reports that liver injury appeared between a few weeks and six months after starting.

    Long unsupervised use is the pattern the reports describe most often. Anyone planning to take giloy for more than a few weeks should agree that with a doctor first.

    Also Read: What Is Shatavari? A Complete Guide to Its Uses and Health Benefits

    What side effects can giloy cause? 

    Giloy Side Effects

    The side effect that matters most is liver injury. LiverTox describes the pattern as hepatocellular, with ALT and AST between 10 and 50 times the upper limit of normal.

    It records more than 50 reported cases since 2017, most of them during the COVID-19 period. Autoantibodies were frequent, sometimes with features of autoimmune hepatitis on liver biopsy.

    Severity ranges widely. LiverTox describes cases from minimally symptomatic enzyme rises, through mild hepatitis that settled on stopping, to severe hepatitis, acute liver failure and deaths.

    What do the liver injury reports say? 

    An Indian case series described six people who developed hepatotoxicity after self-medicating with giloy. The Ayurveda community responded that the patients had probably taken Tinospora crispa, a look-alike species known to harm the liver. The authors then confirmed by DNA analysis[6] that the plant taken was Tinospora cordifolia. They concluded it had caused an autoimmune-like hepatitis, or unmasked a latent autoimmune liver disease.

    A rebuttal in the same journal[7] argued the other way. It cites animal work finding the aqueous extract non-toxic up to 2,000 mg per kg by mouth. It also cites a trial in healthy volunteers taking 500 mg for 21 days, with normal results. It adds that diabetes and hypothyroidism, and the medicines used for them, are confounders, and that baseline liver function was not reported.

    A 2023 case report in Cureus[8] sits with the first group. A woman taking a supplement containing 900 mg of Tinospora cordifolia extract developed symptoms after four to five weeks, with ALT at 1,336. Stopping it, with a short course of prednisone, returned her liver tests to baseline within three months.

    LiverTox has since given Tinospora its highest likelihood score, listing it as a well established cause of clinically apparent liver injury. Where sources disagree this way, the useful response is not to pick a side but to know the warning signs.

    Who should be careful with giloy? 

    Situation What to do
    Existing liver disease LiverTox reports that cases appear more frequent and more severe in people with pre-existing liver disease, often as acute-on-chronic injury that worsens the underlying condition. Giloy should not be started without a doctor’s agreement.
    An autoimmune condition The Cureus patient had Hashimoto’s thyroiditis, and the authors suggest autoimmune disease deserves further investigation as a risk factor.
    Long unsupervised courses LiverTox puts time to onset between a few weeks and six months. The published cases describe self-medication rather than prescribed courses.
    Raw stem bought loose Tinospora crispa resembles Tinospora cordifolia and is known to harm the liver. Loose stem carries an identification risk that a labelled product does not.
    New symptoms while taking it Fresh tiredness, nausea, loss of appetite, dark urine or yellowing of the eyes is a reason to stop giloy and see a doctor that week.

    Can giloy interact with other medicines? 

    No formal interaction studies were retrieved for this article.

    The nearest thing the sources offer is indirect. People taking medicines for diabetes and hypothyroidism were among those in the liver injury cases, which the rebuttal treats as a confounder rather than an interaction.

    That is a reason to tell a prescriber what you are taking rather than to assume the two are unrelated.

    Where can you buy giloy online? 

    Medkart lists giloy products in its Ayurvedic range. Guduchi capsules from Himalaya Wellness carry Tinospora cordifolia extract, and Shanshamani Vati from Zandu is built on the same herb.

    Giloy also appears inside combination formulations. Kofol Immunity tablets and Ojus syrup both list Guduchi among their herbs, and Immumor syrup lists Giloy alongside tulsi and ashwagandha.

    The Ayurvedic products category and the Ayurvedic composition listing show what is stocked, and Medkart’s medicine comparison tool places products side by side. Medkart states that the medicines it sells are sourced from WHO-GMP certified manufacturers.

    Giloy products appear in the medicines index and are sold without a prescription, so a doctor or pharmacist should be told before one is added to regular medicines.

    Key takeaways 

    • Giloy is Tinospora cordifolia, known in Ayurveda as Guduchi.
    • Its traditional uses are wide, and the evidence tested in people is much narrower.
    • A 2023 review states that large-scale clinical studies are still needed to prove efficacy.
    • LiverTox records a typical dose of 400 to 1,000 mg daily for products sold over the counter.
    • No source retrieved for this article gives a best time of day to take it.
    • LiverTox lists Tinospora as a well established cause of clinically apparent liver injury.
    • A published case series and a published rebuttal disagree about how strong that link is.
    • Fresh tiredness, nausea, dark urine or yellow eyes while taking giloy calls for stopping and seeing a doctor.

    FAQs: Common Questions About Giloy 

    Q. Is giloy the same thing as Guduchi? 

    Yes. LiverTox records giloy as the Hindi name and Guduchi as the Sanskrit name for the same plant. Guduchi is the form used on most Indian product labels, and seeing both on one pack does not mean two ingredients.

    Q. Is giloy juice as effective as giloy tablets? 

    No retrieved source compares the forms against each other. LiverTox gives a single dose range of 400 to 1,000 mg daily across solutions, powders, capsules and tablets together, rather than a separate figure for each form. The choice between a juice and a tablet is therefore not one the published evidence settles.

    Q. How soon after starting giloy could liver trouble appear? 

    Not immediately, which is part of why it gets missed. The Cureus patient developed symptoms after four to five weeks. Someone who has taken it for a fortnight without trouble has not cleared the window.

    Q. Does stopping giloy reverse the liver injury? 

    Usually, though not always. LiverTox describes the injury as typically self-limited, with chronic damage not clearly described. The same source also records severe hepatitis, acute liver failure and deaths, so this is not a reason to wait and see.

    Q. Is a labelled tablet safer than raw giloy stem? 

    On identification, yes. A labelled product from a known manufacturer names the species it contains, and a bundle of stem bought loose does not. Since a look-alike species is known to harm the liver, knowing which plant is in the pack is the practical difference.

    Q. Can giloy be taken to prevent colds and flu? 

    No source retrieved for this article supports that. The published human trial was in HIV-positive patients and measured symptoms and blood counts. Immune-modulatory activity in a laboratory is a different claim from preventing an illness in a person.

    Q. Should someone already taking giloy stop? 

    That is a decision for their doctor, not for an article. What the sources support is knowing the warning signs, avoiding long unsupervised courses, and being more cautious where there is existing liver disease or an autoimmune condition. Anyone with symptoms should stop and seek advice rather than finish the pack.

    References 

    Medical disclaimer: This article gives general information only. It does not replace advice from a doctor or pharmacist. No medicine or supplement should be started, stopped or changed without advice from the prescriber or a qualified pharmacist.

  • PCOD (PCOS): Symptoms, Causes, Diagnosis and Treatment

    PCOD (PCOS): Symptoms, Causes, Diagnosis and Treatment

    PCOD is the name Indian readers search for when periods turn irregular, unwanted hair appears, or pregnancy is not happening. It names a hormone condition rather than a test result.

    The name needs sorting out first, because it has changed.

    What does PCOD stand for, and what is it called now? 

    Nothing the sources use. None of them uses PCOD, and the condition’s clinical name has recently changed. The NHS[1] now calls it polyendocrine metabolic ovarian syndrome, or PMOS, and states that PMOS used to be called polycystic ovary syndrome, or PCOS.

    Not every source has moved. The World Health Organization[2] fact sheet still uses polycystic ovary syndrome. MedlinePlus[3] gives the alternative names as PCOS and Stein-Leventhal syndrome.

    No source retrieved for this article treats PCOD as a clinical term, so this article uses the names the sources use.

    MedlinePlus describes a set of symptoms caused by a hormone imbalance, and the NHS states there is no cure but treatments can help.

    What are the symptoms of PCOD? 

    PCOD Symptoms

    They cluster around periods, hair, skin and fertility, and vary widely.

    Feature What the sources say
    Periods The NHS lists irregular periods or long gaps between them. The WHO adds that periods may be absent altogether, and that some people have heavy, long or painful ones.
    Hair The NHS lists excess hair growth, called hirsutism, and also hair loss. The WHO describes female-pattern baldness or thinning alongside excess facial or body hair.
    Skin Oily skin and acne appear on both lists. The NHS also names thick, dark patches of skin, called acanthosis nigricans.
    Fertility Both name difficulty getting pregnant.
    Mood and energy The NHS lists mental health problems including depression and anxiety, and feeling very tired.

    These are features the sources associate with the condition, not a test anyone can apply to themselves.

    What causes PCOD? 

    PCOD Causes

    Nobody knows. Both the NHS and the WHO state plainly that the cause is unknown.

    What they describe instead are things that travel with it. The NHS says it may involve hormones such as insulin and testosterone not working properly, and notes a link with family history. MedlinePlus names genetics, raised androgen levels and insulin resistance, and the WHO adds that a family history of type 2 diabetes also raises risk.

    How is PCOD diagnosed? 

    PCOD Diagnosis or tests

    By meeting two of three criteria, after tests a doctor arranges. The WHO gives the three as signs of high androgens, irregular or absent periods, and polycystic ovaries on ultrasound.

    The 2023 international guideline[4] keeps that structure and adds one option: in adults, a blood test for anti-Müllerian hormone may replace the ultrasound. It says that test should not be used alone, and that both it and the scan should not be done, to limit over-diagnosis.

    The guideline advises against the scan in adolescents.

    The NHS describes the practical route: blood tests for hormone levels and insulin resistance, and an ultrasound scan of the ovaries for patients over 18.

    How common is PCOD in India? 

     PCOD Common in India

    Common, and Indian estimates differ sharply depending on the criteria applied. An Indian Council of Medical Research task force study[5] assessed 8,993 women aged 18 to 40 across eight states, published in JAMA Network Open in 2024.

    It found a weighted national prevalence of 7.2 per cent by the older NIH 1990 criteria, and 19.6 per cent by the Rotterdam 2003 criteria. Among the women who met the criteria, 91.9 per cent had dyslipidaemia.

    A 2022 systematic review in Cureus[6] pooled eleven Indian studies and gave lower figures: 11.33 per cent by Rotterdam and 5.8 per cent by NIH criteria. The WHO estimates 10 to 13 per cent of reproductive-aged women worldwide are affected.

    Also Read: Maximum Delay in Periods if not Pregnant: How Long is Normal?

    How is PCOD treated? 

    PCOD Treatment

    There is no cure, and treatment targets whichever features are causing trouble. The WHO states that treatments can improve quality of life, assist with fertility, and reduce endometrial cancer risk.

    For irregular cycles and excess hair growth, the guideline names combined oral contraceptive pills as first-line drug treatment in adults. The NHS also lists the progestogen-only pill and the intrauterine system.

    Metformin has a narrower place: the guideline says it should be considered in adults with a body mass index of 25 kg/m² or above. It adds that metformin and active lifestyle intervention have similar efficacy.

    Where the difficulty is getting pregnant, the guideline names letrozole as the first-line drug for ovulation induction. The NHS lists clomifene and laparoscopic ovarian drilling.

    Every one of these is a prescription decision.

    How is PCOD managed with diet and exercise? 

    PCOD diet and exercise

    With both, and the guideline is unusually clear that the benefit does not depend on losing weight.

    It recommends lifestyle intervention for everyone with the condition, whether exercise alone or diet and exercise with behavioural strategies.

    On amount, the guideline points to general population targets: 150 to 300 minutes a week of moderate activity, or 75 to 150 of vigorous, plus muscle-strengthening twice weekly.

    The two sources differ on intensity. The guideline finds no evidence that one type or intensity beats another, while the NHS advises avoiding high-intensity exercise because it can make symptoms worse.

    The guideline also records that many women with the condition meet weight stigma in healthcare, and says the harm that does should be recognised.

    Is there a recommended diet for PCOD, and foods to avoid? 

    No single diet, and no list of foods to avoid. The guideline finds no evidence that one diet composition beats another for metabolic, hormonal, reproductive or psychological outcomes.

    It recommends any composition consistent with healthy-eating guidelines, tailored to the person’s own food preferences. The NHS advice is a balanced diet, with weight loss suggested where someone is overweight.

    When should you see a doctor? 

    See a doctor if you think you might have the condition, or if symptoms are affecting your everyday life, work and relationships. That is the NHS threshold, and it does not require every feature above.

    Situation What to do
    Periods that are irregular, very infrequent or have stopped Raise it at an appointment rather than waiting. The 2023 guideline records that premenopausal women with the condition have a markedly higher risk of endometrial hyperplasia and endometrial cancer.
    Difficulty getting pregnant Both the NHS and the WHO list this among the reasons to seek help, and the fertility treatments named above all need a prescriber.
    Excess hair growth, hair loss or acne affecting daily life The NHS names these among the symptoms to see a GP about where they affect everyday life.
    Low mood or anxiety The NHS lists mental health problems among the features of the condition, and the same threshold applies.
    A family history of type 2 diabetes Mention it. The guideline records raised risk of impaired glucose tolerance and type 2 diabetes regardless of body mass index.

    Do not wait until the list is complete. The WHO estimates around 70 per cent of affected women worldwide are undiagnosed.

    What this article cannot tell you 

    Whether you have it. The diagnosis needs two of three criteria, and two of those three need a blood test or a scan.

    It also cannot say which treatment suits any individual, because everything named above is addressed to clinicians. The choice depends on age, test results, whether pregnancy is wanted, and other conditions.

    The 2023 guideline was published before the renaming, so it uses PCOS throughout, as does the WHO fact sheet.

    Where can you buy prescribed medicines on Medkart? 

    Every medicine named above is prescription-only, so this is about filling a prescription rather than choosing a treatment.

    Medkart lists products whose labels name PCOS, and each is marked as needing a prescription. Four are built on inositol: Mychiro tablets from USV, Myocyst M from Akums, which pairs it with sustained-release metformin, Met PCO Care from Akumentis, and Ovagrace sachets from Mankind.

    Metformin is listed on its own too, as Glycomet tablets from USV. Nothing here says any of these treats the condition. Availability, pack size and price differ between products and can change.

    Medkart states that the medicines it sells are sourced from WHO-GMP certified manufacturers. Medkart’s medicine comparison tool sets products side by side once something has been prescribed, and the medicines index and search page show current stock. Points worth comparing on a prescription:

    • Active ingredient
    • Strength
    • Dosage form
    • Manufacturer
    • Pack size

    Nothing listed here should be started, stopped or changed without the prescriber’s advice.

    Key takeaways 

    • The NHS now calls the condition polyendocrine metabolic ovarian syndrome, and says it used to be called polycystic ovary syndrome.
    • The WHO fact sheet and the 2023 international guideline still use the name PCOS.
    • No source retrieved for this article uses PCOD as a clinical term.
    • Diagnosis needs two of three criteria, and a doctor arranges the tests that settle them.
    • An Indian task force study found a national prevalence of 7.2 per cent by NIH criteria and 19.6 per cent by Rotterdam criteria.
    • There is no cure, and treatment targets whichever features are causing trouble.
    • The guideline names lifestyle change for everyone with the condition, and says the benefit does not depend on weight loss.
    • Irregular periods, difficulty conceiving, or symptoms affecting daily life are all reasons to see a doctor.

    FAQs: Common Questions About PCOD 

    Q. Do you need cysts on your ovaries to have it? 

    No, and that is part of what the new name is getting at. The scan finding is one of three criteria, and only two are needed, so the diagnosis can be made without it.

    Q. Is yoga recommended for PCOD? 

    Not by any source retrieved for this article. The 2023 guideline does not mention yoga, meditation or other mind-body practices, and neither the NHS nor the WHO fact sheet names them. That is silence rather than a finding against yoga, so this article cannot say what it does for the condition.

    Q. Can teenagers be diagnosed with it? 

    With more caution than adults. The 2023 guideline states there are no definitive criteria for polycystic ovary morphology on ultrasound in adolescents. Where features are present but the full criteria are not met, it advises reassessment at or before eight years after the first period.

    Q. Does it always cause weight gain? 

    No. Weight gain and difficulty losing weight sit on the NHS symptom list, but they are not universal. In the Indian task force study, 43.2 per cent of the women who met the criteria had obesity, so most did not. The guideline records raised diabetes risk regardless of body mass index.

    Q. What other health checks might a doctor suggest? 

    Metabolic and cardiovascular ones. The guideline considers women with the condition at increased cardiovascular risk, and notes more obstructive sleep apnoea independent of body mass index. The NHS adds high blood pressure and non-alcoholic fatty liver disease.

    Q. Why do Indian prevalence figures differ so much? 

    Because the criteria count different things. The NIH 1990 definition is narrower than the Rotterdam 2003 definition, so the same population yields a smaller number. Hence one study reporting both 7.2 and 19.6 per cent for the same women.

    Q. Does it affect only the ovaries? 

    No, which is the reason behind the new name. MedlinePlus describes hormone imbalance affecting the ovaries and many other body systems. The NHS names hair growth, periods, fertility and mood among the things it touches.

    References 

    Medical disclaimer: This article gives general information about polycystic ovary syndrome, now also called polyendocrine metabolic ovarian syndrome, and is not a diagnosis. It cannot tell any individual whether they have the condition, how severe it is, or which treatment suits them, because those decisions need a doctor and the right tests. Anyone with the symptoms described here should see a doctor rather than self-treat, and no medicine or supplement should be started, stopped or changed without advice from the prescriber or a qualified pharmacist.

  • Ciprofloxacin: Uses, Dosage, Side Effects & Precautions

    Ciprofloxacin: Uses, Dosage, Side Effects & Precautions

    Ciprofloxacin is the generic name of an antibiotic used for certain bacterial infections. It is a prescription medicine in India, sold under several brand names as tablets and as a liquid.

    Those tablets are made by many different companies. The active ingredient is the same across them, but the strength, pack size and price are not.

    What is ciprofloxacin? 

    Ciprofloxacin

    Ciprofloxacin is an antibiotic. MedlinePlus[1] places it in a class of antibiotics called fluoroquinolones and explains that it works by killing bacteria that cause infections.

    The NHS[2] describes it as a broad-spectrum antibiotic available only on prescription. The same page says the tablets and liquid are used only when no other antibiotic is suitable, because of a risk of serious and long-term side effects.

    Its status in India is set by the Drugs Rules, 1945[3]. Ciprofloxacin hydrochloride appears at entry 113 in Schedule H, the schedule of prescription drugs. Rule 97 requires the pack to carry the symbol Rx and a warning against retail sale without a doctor’s prescription.

    What are the main ciprofloxacin uses? 

    ciprofloxacin uses

    Ciprofloxacin is used for certain bacterial infections. MedlinePlus says it treats or prevents them, and names plague and inhalation anthrax among the infections covered.

    DailyMed’s label[4] lists a long set of approved adult uses. They include urinary tract infections, lower respiratory tract infections, acute sinusitis, skin infections, bone and joint infections, infectious diarrhoea and typhoid fever.

    The NHS names urinary tract infections, chest infections including pneumonia, skin and bone infections, sexually transmitted infections, and eye and ear infections.

    Popular brands containing ciprofloxacin 

    Several ciprofloxacin brands are sold in India. The company names below are those shown on the Medkart listing for each pack.

    Brand Name Active Ingredient Available Strengths / Forms* Manufacturer / Company
    Ciplox Ciprofloxacin 250 mg and 500 mg tablets Cipla Pharmaceutical Company Limited
    Cifran Ciprofloxacin 500 mg tablets Sun Pharmaceutical Industries Ltd
    Ciprobid Ciprofloxacin 500 mg tablets Cadila Pharmaceuticals Private Limited
    Ciprodac Ciprofloxacin 500 mg tablets Cadila Pharmaceuticals Private Limited
    Alcipro Ciprofloxacin 500 mg tablets Alkem Laboratories Limited
    Zoxan Ciprofloxacin 500 mg tablets F D C India Limited

    Examples of listed strengths and forms, not a complete catalogue. Product ranges can change.

    Availability and pack size differ between products. The range sold under any one brand can change.

    How is ciprofloxacin dosage decided? 

    There is no one dose that applies to every ciprofloxacin prescription. The infection, its severity and kidney function all come into it.

    NHS guidance on how and when to take ciprofloxacin[5] describes tablets of 100 mg, 250 mg, 500 mg and 750 mg. There is also a liquid containing 250 mg in 5 ml. It gives a usual range of 250 mg to 750 mg twice a day. Children and people with kidney problems take lower amounts.

    A strength such as ciprofloxacin 500 mg describes the amount of active ingredient in that product. It is product information, not a dosing instruction.

    DailyMed sets different amounts and durations for each infection. For an acute uncomplicated urinary tract infection it gives 250 mg every 12 hours for three days. What applies to one person is a decision for the prescriber.

    Why does antibiotic resistance matter? 

    ciprofloxacin antibiotic resistance

    Resistance grows when antibiotics are used where they are not needed. DailyMed states that using ciprofloxacin only for infections that are proven or strongly suspected to be bacterial reduces the development of drug-resistant bacteria.

    MedlinePlus states that antibiotics such as ciprofloxacin will not work for colds, flu or other viral infections. It advises taking the medicine until the prescription is finished, even when the person feels better.

    NHS guidance on common questions about ciprofloxacin[6] says it is very important to keep taking it until the course is finished. It also says a doctor should be told if there is no improvement after two to three days, or if things get worse at any point.

    Also Read: Doctors must mention Reason while Prescribing Antibiotics

    What are the common ciprofloxacin side effects? 

    ciprofloxacin side effects

    Feeling sick and diarrhoea are the most commonly reported effects. NHS guidance on ciprofloxacin side effects[7] reports them in more than 1 in 100 people, along with a bad taste in the mouth.

    MedlinePlus lists nausea, vomiting, diarrhoea, stomach pain, heartburn, pale skin and unusual tiredness among its common effects.

    The NHS lists serious effects that happen in less than 1 in 100 people, and says to stop the medicine and contact a doctor about any of them, including:

    • Pain or swelling in joints or tendons, often starting in the ankle or calf
    • Pins and needles, tingling, numbness or burning pain, especially in the legs or arms
    • Mood or behaviour changes, confusion, or problems with memory
    • Diarrhoea with blood or mucus
    • An irregular or fast heartbeat, or sudden breathlessness

    DailyMed adds that diarrhoea caused by Clostridioides difficile can appear months after treatment ends, and that skin can react strongly to sun or ultraviolet light during treatment.

    Why the fluoroquinolone warnings matter 

    Ciprofloxacin carries a boxed warning covering four risks. DailyMed names tendinitis and tendon rupture, peripheral neuropathy, central nervous system effects, and worsening of muscle weakness in myasthenia gravis.

    MedlinePlus states that the tendon risk runs during treatment and for up to several months afterwards. It adds that nerve damage may not go away after the medicine is stopped. DailyMed advises avoiding ciprofloxacin in anyone with a known history of myasthenia gravis.

    The European Medicines Agency[8] restricted this class of antibiotics after reviewing disabling and potentially long-lasting side effects. It advises stopping a fluoroquinolone and contacting a doctor at once at the first sign of tendon pain, joint swelling or nerve symptoms. The NHS states that ciprofloxacin is not prescribed for more than three months at a time.

    Who should be careful with ciprofloxacin? 

    Most people can take it, but several situations need raising first. NHS guidance on who can and cannot take ciprofloxacin[9] says most adults and children aged 1 year and over can take or use it.

    Situation What to do
    A previous reaction to a fluoroquinolone The NHS says to speak to a doctor first after any allergic reaction to ciprofloxacin, or any serious side effect with ciprofloxacin or another fluoroquinolone. DailyMed contraindicates it after hypersensitivity to ciprofloxacin or any quinolone.
    Myasthenia gravis DailyMed’s boxed warning covers worsening muscle weakness, and it says ciprofloxacin should be avoided in anyone with a known history of the condition.
    Aorta problems The NHS says to speak to a doctor first about an abdominal aortic aneurysm or another aorta problem, including where a family member has had one.
    Heart rhythm problems The NHS lists a fast, pounding or irregular heartbeat among the situations to raise before starting.
    Mental health conditions The NHS says to mention depression, anxiety, suicidal feelings or any other mental health condition first.
    Epilepsy, kidney problems or diabetes The NHS lists all three, and notes that ciprofloxacin can affect blood sugar.
    Tendon or connective tissue disorders The NHS lists previous tendon problems, rheumatoid arthritis, Behcet’s disease and Marfan syndrome among the situations to raise first.

    The NHS also says to mention pregnancy, plans to become pregnant, or breastfeeding. DailyMed contraindicates ciprofloxacin alongside tizanidine.

    Generic ciprofloxacin vs brand-name ciprofloxacin 

    Generic ciprofloxacin vs brand-name ciprofloxacin

    Generic and branded ciprofloxacin contain the same active ingredient. The US FDA[10] states that a generic medicine matches the brand-name medicine on active ingredient, strength, dosage form and route of administration, and is bioequivalent to it.

    The FDA adds that approved generics provide the same clinical benefit and risks as their brand-name counterparts. That is the U.S. FDA standard, and an India-specific regulatory source is needed before making the same claim about an Indian product.

    Products can still differ in manufacturer, inactive ingredients, appearance and price. The same active ingredient and strength alone do not prove that two products are interchangeable. A doctor or pharmacist should confirm any switch between brands.

    Buy or compare ciprofloxacin tablets on Medkart 

    Medkart sells ciprofloxacin products online from several manufacturers and lists them as prescription items. Its composition listings for ciprofloxacin 500 mg and ciprofloxacin 250 mg show what is stocked at each strength. Medkart states that the medicines it sells are sourced from WHO-GMP certified manufacturers.

    Medkart’s medicine comparison tool places products side by side, and the medicines index lists what is in stock. The details a reader can compare include:

    • Active ingredient
    • Strength
    • Dosage form
    • Manufacturer
    • Pack size
    • Current price

    Any suggested alternative should be discussed with a doctor or pharmacist before changing a prescribed antibiotic.

    Key takeaways 

    • Ciprofloxacin is an antibiotic in the fluoroquinolone group and works by killing bacteria.
    • Ciprofloxacin hydrochloride is listed at entry 113 in Schedule H of India’s Drugs Rules, 1945, which makes it a prescription drug.
    • The NHS states that ciprofloxacin tablets and liquid are used only when no other antibiotic is suitable.
    • A strength such as ciprofloxacin 500 mg is product information, not an instruction about how much to take.
    • Feeling sick and diarrhoea are among the most commonly reported side effects.
    • The boxed warning covers tendinitis and tendon rupture, nerve damage, central nervous system effects and worsening of myasthenia gravis.
    • Tendon pain, joint swelling or nerve symptoms are a reason to stop the medicine and contact a doctor at once.
    • Antibiotics do not work for colds, flu or other viral infections, and a prescribed course is meant to be finished.

    FAQs: Common Questions About Ciprofloxacin 

    Q. How quickly does ciprofloxacin start working? 

    Most people feel better within a few days. NHS guidance on common questions says how quickly it works depends on the infection. A bone infection can take a week or longer before there is any improvement. A doctor is the right person to tell if progress is slower than expected.

    Q. What happens if a dose of ciprofloxacin is missed? 

    It depends on how close the next dose is. NHS guidance on how and when to take ciprofloxacin says a missed dose should be taken as soon as it is remembered, unless the next one is nearly due. In that case the missed dose is skipped and the normal schedule resumes. The same guidance says never to take a double dose to catch up.

    Q. Why should dairy products be avoided around a dose? 

    Because they can stop the medicine working properly. NHS guidance on how and when to take ciprofloxacin says to avoid dairy products such as milk, cheese and yoghurt, because they affect how the medicine works. The same guidance says the tablets should be swallowed whole with plenty of water rather than chewed.

    Q. Is it safe to drink alcohol while taking ciprofloxacin? 

    Yes. NHS guidance on common questions about ciprofloxacin states that alcohol can be drunk while taking it. Anyone unsure how that sits with their other medicines should ask a pharmacist.

    Q. Can ciprofloxacin be given to a child? 

    Sometimes, and only on a prescription. The NHS says most adults and children aged 1 year and over can take or use ciprofloxacin. DailyMed approves it for children aged 1 to 17 years for complicated urinary tract infections and kidney infections. It notes a higher rate of joint and tissue problems in children. A doctor decides whether it is the right choice.

    Q. What happens if too much ciprofloxacin is taken? 

    It can cause harm. The NHS says taking too much ciprofloxacin can cause feeling sick, being sick, diarrhoea, an irregular heartbeat, or seizures in people with epilepsy. Anyone who has taken more than the prescribed amount should contact a doctor, a pharmacist or a hospital straight away.

    References 

    Medical disclaimer: This article provides general information and does not replace advice from a doctor or pharmacist. Ciprofloxacin is an antibiotic listed in Schedule H of India’s Drugs Rules, 1945, so ciprofloxacin products in India are prescription medicines. Brands with the same composition should only be substituted under the guidance of a healthcare professional or pharmacist because product details and approved indications can differ.

  • Chamomile Tea: Benefits, Uses, How to Make It and Side Effects

    Chamomile Tea: Benefits, Uses, How to Make It and Side Effects

    Chamomile tea is an infusion made by pouring boiling water over the dried flower heads of the chamomile plant. In India the plant is a permitted nutraceutical ingredient, and in Europe the flower is a registered traditional herbal medicine.

    The plant behind almost all of it is Matricaria recutita, also written Matricaria chamomilla and known as German chamomile. Most human trials on chamomile tested a concentrated extract in a capsule rather than the drink.

    What is chamomile tea? 

    Chamomile tea

    Chamomile tea is an infusion of dried chamomile flower heads in hot water. The European Medicines Agency[1] defines the herbal substance as Matricaria recutita L., flos, meaning the flower and no other part of the plant.

    What people use it for is broader than what it is registered for. The National Center for Complementary and Integrative Health[2] lists the common cold, indigestion, anxiety and insomnia among the things chamomile is promoted for.

    What are the benefits and uses of chamomile tea? 

    benefits and uses of chamomile tea

    The EMA recognises chamomile flower for a small set of minor complaints, and only as a traditional herbal medicine.

    Only one of the five registered uses involves drinking the infusion. The others are a mouth rinse, a skin wash, a local irrigation and a steam inhalation.

    Use What the evidence says
    Minor digestive complaints The EMA registers the flower, taken by mouth as an infusion, for minor gastro-intestinal complaints such as bloating and minor spasms. The registration rests on long-standing use, not on trial results.
    Anxiety A trial in the Journal of Clinical Psychopharmacology[3] randomised 57 outpatients with mild to moderate generalised anxiety disorder to a standardised extract or placebo for eight weeks. Anxiety scores fell further on chamomile, at p equal to 0.047. The trial used capsules, not tea.
    Mouth and throat The EMA registers an infusion of 1 to 5 g in 100 ml of water for minor ulcers and inflammation of the mouth and throat, used for rinsing and gargling rather than swallowed.
    Skin and sunburn It also registers the flower for minor skin inflammation including sunburn, superficial wounds and small boils, applied as a wash or an impregnated dressing.
    Common cold For cold symptoms the monograph gives 3 to 10 g in 100 ml of hot water as a steam inhalation, which is not a drinking use.

    Does chamomile tea help with weight loss? 

    No. Weight is not among the uses the EMA registers. A 2021 review of chamomile in obesity and metabolic syndrome[4] states that no clinical trials of chamomile in the management of obesity were available to its authors.

    The review describes laboratory and animal work on carbohydrate digestion and energy metabolism instead. Its authors treat chamomile as a promising candidate, while noting that any effect is likely to be moderate because plant polyphenols are poorly absorbed when swallowed.

    How do you make chamomile tea? 

    chamomile tea Making Tips

    As an infusion. The EMA’s patient leaflet template for herbal teas[5] sets out the method in standard terms.

    Boiling water is poured over the flowers, and the tea is left to steep for a set period, usually 5 to 15 minutes where nothing else is specified. The vessel is kept covered with a lid and stirred at intervals. The liquid is then strained through a tea strainer.

    The same document notes that infusion suits leaves, flowers and delicate plant parts, while roots and barks are simmered or soaked instead.

    What is the recommended dosage of chamomile tea? 

    There is no one amount that applies to everyone. For the flower brewed as a tea, the monograph gives adolescents, adults and the elderly a single dose of 1.5 to 4 g in 150 ml of boiling water. It puts the frequency at 3 to 4 times a day.

    Smaller single doses are set out for children, taken 2 to 4 times a day:

    • 6 months to 2 years: 0.5 to 1.0 g
    • 2 to 6 years: 1.0 to 1.5 g
    • 6 to 12 years: 1.5 to 3.0 g

    A weight printed on a pack of tea bags describes how much flower each bag holds. It is product information, not an instruction about how much to drink.

    India regulates the ingredient rather than the brew. The Food Safety and Standards Authority of India[6] lists Matricaria chamomilla as a permitted nutraceutical ingredient in Schedule VI, Part B. The entry covers an aerial parts extract, sets no daily range, and describes a manufactured product rather than flowers brewed at home.

    When should you drink chamomile tea? 

    No source retrieved for this article gives a best time of day. The monograph sets a frequency of 3 to 4 times daily and says nothing about morning or evening.

    Does chamomile tea help with sleep? 

    Sleep is why people ask, and the sources disagree.

    The NCCIH reports that a 2019 review found only one insomnia study, and that it showed no benefit. A pilot trial in BMC Complementary and Alternative Medicine[7] gave 34 adults with chronic primary insomnia 270 mg of chamomile extract twice daily for 28 days. Total sleep time and sleep efficiency did not differ significantly from placebo, though time to fall asleep shortened by about 16 minutes.

    A trial in the Journal of Education and Health Promotion[8] found the opposite. Seventy-seven nursing home residents aged over 60 took 400 mg capsules twice daily, after lunch and after dinner, for four weeks. Sleep quality scores improved against the control group, and the authors name the absence of blinding and of a placebo group among the study’s limits.

    All three used capsules of extract, so their schedules are not schedules for a cup of tea.

    Also Read: Ashwagandha for Men: Benefits for Energy, Strength & Hormones

    How long can you drink chamomile tea? 

    The EMA sets a checkpoint rather than a maximum. If symptoms last more than one week, the monograph says a doctor or a qualified health care practitioner should be consulted. The same applies if symptoms get worse.

    No source retrieved for this article sets a limit on chamomile drunk as an ordinary beverage.

    What side effects can chamomile tea cause? 

     chamomile tea side effects

    Allergic reactions are the effect the sources single out. The EMA records hypersensitivity reactions, including severe ones, and puts their frequency at not known.

    Among the severe reactions it names breathlessness, Quincke’s disease, vascular collapse and anaphylactic shock. These were reported after mucosal contact with liquid chamomile preparations.

    The NCCIH describes chamomile as likely safe by mouth in the amounts commonly found in teas and other foods. It lists nausea, dizziness and allergic reactions as uncommon effects. The EMA adds that no case of overdose has been reported.

    Who should be careful with chamomile tea? 

    The clearest case is an allergy to plants in the daisy family. Four other situations call for care.

    Situation What to do
    An allergy to daisies, marigolds or ragweed The EMA contraindicates chamomile in anyone with hypersensitivity to it or to other plants of the Asteraceae family. The NCCIH notes that reactions are more likely in people allergic to ragweed, chrysanthemums, marigolds or daisies.
    Pregnancy and breastfeeding The sources disagree. The EMA states that safety during pregnancy and lactation has been established for the comminuted flower used as a tea, but not for the extracts, whose use it does not recommend. The NCCIH says little is known about either.
    Babies under six months The EMA has not established oral use of the herbal tea below six months of age, on general grounds of nutrition and fluid intake.
    Regular prescribed medicines Interactions have been reported for concentrated preparations. A pharmacist should be told what is being taken before chamomile becomes a daily habit.
    Hormonal contraception The NCCIH notes that chamomile may have oestrogen-like effects, and that these might reduce the effectiveness of birth control pills.
    Breathlessness, swelling or faintness after drinking it The EMA lists these among reported severe reactions. They call for stopping the tea and getting medical help the same day.

    Can chamomile tea interact with medicines? 

    Possibly, and what has been reported involves concentrated preparations rather than a cup. The EMA reports interactions based on effects on CYP450 in patients after kidney transplantation who took high doses for about two months. For skin, mouth, inhalation and bath use it reports none.

    The NCCIH reports interactions between chamomile and warfarin, a blood thinner, and with some medicines that the liver breaks down.

    Neither source describes an interaction study on chamomile tea at ordinary drinking strength.

    Where can you buy chamomile tea online? 

    Medkart is a pharmacy, so chamomile appears there mostly as an ingredient inside a formulated product.

    Periods Care tea bags from Taparia Tea Company name chamomile among their herbs. On the skin side, Dermsilk cream from Cure N Cure Pharmaceutical and Urtiplex lotion from Charak Pharmaceuticals both list chamomile extract. So does Gentle Baby Shampoo from Himalaya Wellness.

    The Ayurvedic products category and the Ayurvedic composition listing show the wider herbal range. Availability, pack size and price differ between products and can change.

    Medkart states that the medicines it sells are sourced from WHO-GMP certified manufacturers. Medkart’s medicine comparison tool places products side by side, while the medicines index and the search page show what is in stock. Points worth comparing on a herbal pack include:

    • Botanical name of the plant
    • Whether the pack is pure chamomile or a blend
    • Weight of flower per bag
    • Manufacturer
    • Pack size

    Chamomile products are sold without a prescription, so a doctor or pharmacist should be told before one joins a set of regular medicines.

    Key takeaways 

    • Chamomile tea is an infusion of the dried flowers of Matricaria recutita, known as German chamomile.
    • The EMA registers it as a traditional herbal medicine, which means the use rests on long-standing use rather than trials.
    • Only one of its five registered uses is a drink, for minor digestive complaints such as bloating and spasms.
    • The monograph gives adults a single dose of 1.5 to 4 g in 150 ml of boiling water, 3 to 4 times a day.
    • An infusion is steeped for 5 to 15 minutes under a lid, then strained.
    • No source retrieved for this article gives a best time of day to drink it.
    • The sleep and anxiety trials used capsules of concentrated extract, not the tea.
    • Allergy is the main reported risk, and it is more likely in people who react to daisies, marigolds or ragweed.

    FAQs: Common Questions About Chamomile Tea 

    Q. Is the chamomile in a tea bag the same as the chamomile in a capsule? 

    No, and the difference matters more than it looks. A tea bag holds the dried flower, while a capsule holds an extract concentrated many times over. The EMA treats them as separate preparations with separate amounts, and reaches different conclusions about them in pregnancy.

    Q. Why does the water need to be boiling? 

    For hygiene as much as for flavour. The EMA’s leaflet template notes that boiling water lowers the microbial load carried by dried plant material, which is not sterile. Water that has gone off the boil does less to that load.

    Q. Can brewed chamomile tea be kept and drunk later? 

    For a short while, and cold. The same EMA template says a herbal infusion should be drunk soon after it is made, and otherwise kept covered in the fridge for no more than 24 hours. A pot left standing at room temperature all day falls outside that advice.

    Q. Is German chamomile the same as Roman chamomile? 

    They are different plants sold under a shared name. The EMA monograph and the FSSAI listing both name Matricaria recutita, and the NCCIH says chamomile refers primarily to German chamomile. No source retrieved for this article covers Roman chamomile, so nothing here should be assumed to apply to it.

    Q. Can chamomile tea replace a prescribed medicine for anxiety or sleep? 

    No. The anxiety trial tested a standardised extract in people with mild to moderate symptoms, and its authors said the findings do not extend to severe cases. The registered use for the drink covers minor digestive complaints and nothing more. Any change to prescribed treatment is a decision for the prescriber.

    Q. Do loose flowers and tea bags need different handling? 

    Slightly. The EMA notes that herbal teas come both loose and in sachets, and gives each a different final step. Loose flowers are stirred and strained, with the residue pressed to yield more liquid. A sachet is gently squeezed instead.

    References 

    Medical disclaimer: This article gives general information only. It does not replace advice from a doctor or pharmacist. No medicine or supplement should be started, stopped or changed without advice from the prescriber or a qualified pharmacist.